Protein expression of BACE1, BACE2 and APP in Down syndrome brains
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Clinical Biochemistry,Biochemistry
Link
http://link.springer.com/content/pdf/10.1007/s00726-007-0618-9.pdf
Reference39 articles.
1. The gene encoding DRAP (BACE2), a glycosylated transmembrane protein of the aspartic protease family, maps to the Down critical region
2. Developmental and aging changes in the expression of amyloid precursor protein in down syndrome brains
3. BACE-2 is overexpressed in Down’s syndrome
4. Expression of β-secretase mRNA in transgenic Tg2576 mouse brain with Alzheimer plaque pathology
5. BACE1 is the major β-secretase for generation of Aβ peptides by neurons
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