1H NMR spectroscopy in the presence of Mosher acid to rapidly determine the enantiomeric composition of amino acid benzyl esters, chirons susceptible to easy racemization-Reference-Cited by-同舟云学术

1H NMR spectroscopy in the presence of Mosher acid to rapidly determine the enantiomeric composition of amino acid benzyl esters, chirons susceptible to easy racemization

Published:2018-09-17 Issue:12 Volume:50 Page:1759-1767
ISSN:0939-4451
Container-title:Amino Acids
language:en
Short-container-title:Amino Acids

Author:

Bolchi Cristiano,Roda Gabriella,Pallavicini Marco

Publisher

Springer Science and Business Media LLC

Subject

Organic Chemistry,Clinical Biochemistry,Biochemistry

Link

http://link.springer.com/article/10.1007/s00726-018-2653-0/fulltext.html

Reference27 articles.

1. Bada JL (1972) Kinetics of racemization of amino acids as a function of pH. J Am Chem Soc 94:1371–1373

2. Bergmeier SC, Cobas AA, Rapoport H (1993) Chirospecific synthesis of (1S,3R9-1-amino-3-(hydroxymethyl)cyclopentane, precursor of carbocyclic nucleoside synthesis. Dieckmann cyclization with an alpha-amino acid. J Org Chem 58:2369–2376

3. Bolchi C, Valoti E, Gotti C, Fasoli F, Ruggeri P, Fumagalli L, Binda M, Mucchietto V, Sciaccaluga M, Budriesi R, Fucile S, Pallavicini M (2015) Chemistry and pharmacology of a series of unichiral analogues of 2-(2-pyrrolidinyl)-1,4-benzodioxane, prolinol phenyl ether, and prolinol 3-pyridyl ether designed as alpha4beta2-nNicotinic acetylcholine receptor agonists. J Med Chem 58:6665–6677

4. Bolchi C, Bavo F, Pallavicini M (2017a) One-step preparation of enantiopure l- or d-amino acid benzyl esters avoiding the use of banned solvents. Amino Acids 49:965–974

5. Bolchi C, Bavo F, Pallavicini M (2017b) Phase diagrams to evaluate the opportunity for enantiomeric enrichment of some nonracemic mixtures of amino acid benzyl esters by crystallization as p-toluenesulfonate salts. Org Process Res Dev 21:1752–1757

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