Chemistry and Pharmacology of a Series of Unichiral Analogues of 2-(2-Pyrrolidinyl)-1,4-benzodioxane, Prolinol Phenyl Ether, and Prolinol 3-Pyridyl Ether Designed as α4β2-Nicotinic Acetylcholine Receptor Agonists-Reference-Cited by-同舟云学术

Chemistry and Pharmacology of a Series of Unichiral Analogues of 2-(2-Pyrrolidinyl)-1,4-benzodioxane, Prolinol Phenyl Ether, and Prolinol 3-Pyridyl Ether Designed as α4β2-Nicotinic Acetylcholine Receptor Agonists

Published:2015-08-18 Issue:16 Volume:58 Page:6665-6677
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bolchi Cristiano¹,Valoti Ermanno¹,Gotti Cecilia²,Fasoli Francesca²,Ruggeri Paola¹,Fumagalli Laura¹,Binda Matteo¹,Mucchietto Vanessa²,Sciaccaluga Miriam³,Budriesi Roberta⁴,Fucile Sergio³⁵,Pallavicini Marco¹

Affiliation:

1. Dipartimento di Scienze Farmaceutiche “Pietro Pratesi”, Università degli Studi di Milano, Via Mangiagalli 25, I-20133, Milano, Italy

2. CNR, Istituto di Neuroscienze, and Dipartimento di Biotecnologie Mediche e Medicina Traslazionale, Università degli Studi di Milano, Via Vanvitelli 32, Milano, I-20129, Italy

3. I.R.C.C.S. Neuromed, Istituto Neurologico Mediterraneo, Via Atinese 18, I-86077, Pozzilli, Isernia, Italy

4. Dipartimento di Farmacia e Biotecnologie, Alma Mater Studiorum, Università di Bologna, Via Belmeloro 6, I-40126, Bologna, Italy

5. Dipartimento di Fisiologia e Farmacologia, Università di Roma La Sapienza, Piazzale Moro 5, 00185 Roma, Italy

Funder

Consiglio Nazionale delle Ricerche

Fondazione Giancarla Vollaro

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00904