In silico and in vivo neuropharmacological evaluation of two γ-amino acid isomers derived from 2,3-disubstituted benzofurans, as ligands of GluN1–GluN2A NMDA receptor
Author:
Funder
consejo nacional de ciencia y tecnología
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Clinical Biochemistry,Biochemistry
Link
https://link.springer.com/content/pdf/10.1007/s00726-021-03108-2.pdf
Reference49 articles.
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2. Alexander SP, Peters JA, Kelly E et al (2017) The concise guide to pharmacology 2017/18: ligand-gated ion channels. Br J Pharmacol 174:S130–S159. https://doi.org/10.1111/bph.13879
3. Baragona F, Lomberget T, Duchamp C et al (2011) Synthesis of 5-substituted 2,3-dihydrobenzofurans in a one-pot oxidation/cyclization reaction. Tetrahedron 67:8731–8739. https://doi.org/10.1016/j.tet.2011.09.020
4. Bergmann R, Kongsbak K, Sørensen PL et al (2013) A unified model of the GABAA receptor comprising agonist and benzodiazepine binding sites. PLoS One 8:e52323. https://doi.org/10.1371/journal.pone.0052323
5. Bhagat K, Singh JV, Pagare PP et al (2020) Rational approaches for the design of various GABA modulators and their clinical progression. Mol Divers. https://doi.org/10.1007/s11030-020-10068-4
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