Retrograde trafficking of AB5 toxins: mechanisms to therapeutics
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics(clinical),Drug Discovery,Molecular Medicine
Link
http://link.springer.com/content/pdf/10.1007/s00109-013-1048-7.pdf
Reference89 articles.
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3. Saenz JB, Doggett TA, Haslam DB (2007) Identification and characterization of small molecules that inhibit intracellular toxin transport. Infect Immun 75:4552–4561
4. Stechmann B, Bai SK, Gobbo E, Lopez R, Merer G, Pinchard S, Panigai L, Tenza D, Raposo G, Beaumelle B et al (2010) Inhibition of retrograde transport protects mice from lethal ricin challenge. Cell 141:231–242
5. Mukhopadhyay S, Linstedt AD (2012) Manganese blocks intracellular trafficking of Shiga toxin and protects against Shiga toxicosis. Science 335:332–335
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