In vitro assessment of farnesoid X receptor antagonism to predict drug-induced liver injury risk
Author:
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00204-020-02804-4.pdf
Reference58 articles.
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2. Aleo MD, Shah F, Allen S et al (2019) Moving beyond binary predictions of human drug-induced liver injury (DILI) towards contrasting relative risk potential. Chem Res Toxicol. https://doi.org/10.1021/acs.chemrestox.9b00262
3. Aleo MD, Shah F, He K, Bonin PD, Rodrigues AD (2017) Evaluating the role of multidrug resistance protein 3 (MDR3) inhibition in predicting drug-induced liver injury using 125 pharmaceuticals. Chem Res Toxicol 30(5):1219–1229. https://doi.org/10.1021/acs.chemrestox.7b00048
4. Altman DG, Bland JM (1994) Diagnostic tests 2: predictive values. BMJ 309(6947):102. https://doi.org/10.1136/bmj.309.6947.102
5. Antherieu S, Chesne C, Li R et al (2010) Stable expression, activity, and inducibility of cytochromes P450 in differentiated HepaRG cells. Drug Metab Dispos 38(3):516–525. https://doi.org/10.1124/dmd.109.030197
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