Dapagliflozin protects against doxorubicin-induced cardiotoxicity by restoring STAT3
Author:
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00204-022-03298-y.pdf
Reference31 articles.
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2. Chang WT, Lin YW, Ho CH, Chen ZC, Liu PY, Shih JY (2021) Dapagliflozin suppresses ER stress and protects doxorubicin-induced cardiotoxicity in breast cancer patients. Arch Toxicol 95(2):659–671. https://doi.org/10.1007/s00204-020-02951-8
3. Chazaud B, Mouchiroud G (2014) Inflamm-aging: STAT3 signaling pushes muscle stem cells off balance. Cell Stem Cell 15(4):401–402. https://doi.org/10.1016/j.stem.2014.09.010
4. Chen SH, Murphy DA, Lassoued W, Thurston G, Feldman MD, Lee WM (2008) Activated STAT3 is a mediator and biomarker of VEGF endothelial activation. Cancer Biol Ther 7(12):1994–2003. https://doi.org/10.4161/cbt.7.12.6967
5. Frias MA, Somers S, Gerber-Wicht C, Opie LH, Lecour S, Lang U (2008) The PGE2-Stat3 interaction in doxorubicin-induced myocardial apoptosis. Cardiovasc Res 80(1):69–77. https://doi.org/10.1093/cvr/cvn171
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