Rho-inhibiting C2IN-C3 fusion toxin inhibits chemotactic recruitment of human monocytes ex vivo and in mice in vivo-Reference-Cited by-同舟云学术

Rho-inhibiting C2IN-C3 fusion toxin inhibits chemotactic recruitment of human monocytes ex vivo and in mice in vivo

Published:2017-09-18 Issue:1 Volume:92 Page:323-336
ISSN:0340-5761
Container-title:Archives of Toxicology
language:en
Short-container-title:Arch Toxicol

Author:

Martin Tobias,Möglich Amelie,Felix Ina,Förtsch Christina,Rittlinger Anne,Palmer Annette,Denk Stephanie,Schneider Julian,Notbohm Lena,Vogel Mona,Geiger Hartmut,Paschke Stephan,Huber-Lang Markus,Barth Holger

Funder

Deutsche Forschungsgemeinschaft

PharmCompNet BW

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://link.springer.com/article/10.1007/s00204-017-2058-y/fulltext.html

Reference43 articles.

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2. Aepfelbacher M, Essler M, Huber E, Czech A, Weber PC (1996) Rho is a negative regulator of human monocyte spreading. J Immunol 157:5070–5075

3. Aktories K (2011) Bacterial protein toxins that modify host regulatory GTPases. Nat Rev Microbiol 9:487–498

4. Aktories K, Frevert J (1987) ADP-ribosylation of a 21–24 kDa eukaryotic protein(s) by C3, a novel botulinum ADP-ribosyltransferase, is regulated by guanine nucleotide. Biochem J 247:363–368

5. Aktories K, Jung M, Böhmer J, Fritz G, Vandekerckhove J, Just I (1995) Studies on the active site structure of C3-like exoenzymes: involvement of glutamic acid in catalysis of ADP-ribosylation. Biochimie 77:326–332

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