Targeting organophosphorus compounds poisoning by novel quinuclidine-3 oximes: development of butyrylcholinesterase-based bioscavengers
Author:
Funder
Hrvatska Zaklada za Znanost
Publisher
Springer Science and Business Media LLC
Subject
Health, Toxicology and Mutagenesis,Toxicology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00204-020-02811-5.pdf
Reference78 articles.
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2. Ashani Y, Leader H, Aggarwal N, Silman I, Worek F, Sussman JL, Goldsmith M (2016) In vitro evaluation of the catalytic activity of paraoxonases and phosphotriesterases predicts the enzyme circulatory levels required for in vivo protection against organophosphate intoxications. Chem Biol Interact 259(Pt B):252–256. https://doi.org/10.1016/j.cbi.2016.04.039
3. Aurbek N, Thiermann H, Eyer F, Eyer P, Worek F (2009) Suitability of human butyrylcholinesterase as therapeutic marker and pseudo catalytic scavenger in organophosphate poisoning: a kinetic analysis. Toxicology 259(3):133–139. https://doi.org/10.1016/j.tox.2009.02.014
4. Bosak A, Primožič I, Oršulić M, Tomić S, Simeon-Rudolf V (2005) Enantiomers of quinuclidin-3-ol derivatives: resolution and interactions with human cholinesterases. Croat Chem Acta 78:121–128
5. Čalić M, Lucić Vrdoljak A, Radić B, Jelić D, Jun D, Kuča K, Kovarik Z (2006) In vitro and in vivo evaluation of pyridinium oximes: mode of interaction with acetylcholinesterase, effect on tabun- and soman-poisoned mice and their cytotoxicity. Toxicology 219:85–96. https://doi.org/10.1016/j.tox.2005.11.003
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