In vitro evaluation of the catalytic activity of paraoxonases and phosphotriesterases predicts the enzyme circulatory levels required for in vivo protection against organophosphate intoxications

Author:

Ashani Yacov,Leader Haim,Aggarwal Nidhi,Silman Israel,Worek Franz,Sussman Joel L.,Goldsmith Moshe

Funder

Defense Threat Reduction Agency

US national Institutes of Health

Israel Ministry of Industry/Office of the Chief Scientist Kamin

Publisher

Elsevier BV

Subject

Toxicology,General Medicine

Cited by 17 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Cyclosarin (GF);Reference Module in Biomedical Sciences;2022

2. Post-VX exposure treatment of rats with engineered phosphotriesterases;Archives of Toxicology;2021-12-28

3. Management and Modulation of Cholinesterase;Toxicology of Organophosphate Poisoning;2021-10-12

4. Catalytic activity and stereoselectivity of engineered phosphotriesterases towards structurally different nerve agents in vitro;Archives of Toxicology;2021-06-23

5. Counteracting poisoning with chemical warfare nerve agents;Archives of Industrial Hygiene and Toxicology;2020-12-01

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