Integration of Food Animal Residue Avoidance Databank (FARAD) empirical methods for drug withdrawal interval determination with a mechanistic population-based interactive physiologically based pharmacokinetic (iPBPK) modeling platform: example for flunixin meglumine administration

Author:

Li Miao,Cheng Yi-Hsien,Chittenden Jason T.,Baynes Ronald E.,Tell Lisa A.,Davis Jennifer L.,Vickroy Thomas W.,Riviere Jim E.,Lin ZhoumengORCID

Funder

National Institute of Food and Agriculture

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Reference86 articles.

1. Anissimov YG, Roberts MS (2014) Mathematical models for topical and transdermal drug products. In: Shah VP, Maibach HI, Jenner J (eds) Topical drug bioavailability, bioequivalence and penetration, 2nd edn. Springer, New York, pp 249–298

2. Baron KT, Hindmarsh AC, Petzold LR, Gillespie B, Margossian C, Metrum Research Group LLC (2018) mrgsolve: simulation from ODE-based population PK/PD and systems pharmacology models. R package version 0.8.12. https://metrumrg.com/try-open-source-tools/ . Accessed 14 Nov 2018

3. Baynes R, Riviere JE (2014) Strategies for reducing drug and chemical residues in food animals: international approaches to residue avoidance, management, and testing. Wiley, Hoboken

4. Bois FY (2010) Physiologically based modelling and prediction of drug interactions. Basic Clin Pharmacol Toxicol 106(3):154–161

5. Bon C, Toutain PL, Concordet D, Gehring R, Martin-Jimenez T, Smith J, Pelligand L, Martinez M, Whittem T, Riviere JE, Mochel JP (2018) Mathematical modeling and simulation in animal health. Part III: using nonlinear mixed-effects to characterize and quantify variability in drug pharmacokinetics. J Vet Pharmacol Ther 41(2):171–183

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3