Phase II randomized trial of weekly and every-3-week ixabepilone in metastatic breast cancer patients

Author:

Smith John W.,Vukelja Svetislava,Rabe Amy,Wentworth-Hartung Nicole,Koutrelakos Nicholas,Shao Spencer H.,Whittaker Thomas,Wang Yunfei,Asmar Lina,McDowell Diane Opatt,Mukhopadhyay Pralay,O’Shaughnessy Joyce

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference23 articles.

1. Bollag DM, McQueney PA, Zhu J, Hensens O, Koupal L, Liesch J, Goetz M, Lazarides E, Woods CM (1995) Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action. Cancer Res 55:2325–2333

2. Fumoleau P, Coudert B, Isambert N, Ferrant E (2007) Novel tubulin-targeting agents: anticancer activity and pharmacologic profile of epothilones and related analogues. Ann Oncol 18(Suppl 5):v9–v15

3. Lee FY, Borzilleri R, Fairchild CR, Kim SH, Long BH, Reventos-Suarez C, Vite GD, Rose WC, Kramer RA (2001) BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy. Clin Cancer Res 7:1429–1437

4. Ayoub JP, Verma Sh, Verma S (2012) Advances in the management of metastatic breast cancer: options beyond first-line chemotherapy. Curr Oncol 19:91–105. doi: 10.3747/co.19.1024

5. Lee FY, Smylka R, Johnston K, Menard K, McGlinchey K, Peterson RW, Wiekesiek A, Vite G, Fairchild CR, Kramer R (2009) Preclinical efficacy spectrum and pharmacokinetics of ixabepilone. Cancer Chemother Pharmacol 63:201–212. doi: 10.1007/s00280-008-0727-5

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