Phase I–II study of the farnesyl transferase inhibitor tipifarnib plus sequential weekly paclitaxel and doxorubicin–cyclophosphamide in HER2/neu-negative inflammatory carcinoma and non-inflammatory estrogen receptor-positive breast carcinoma

Author:

Andreopoulou Eleni,Vigoda Ivette S.,Valero Vicente,Hershman Dawn L.,Raptis George,Vahdat Linda T.,Han Hyo S.,Wright John J.,Pellegrino Christine M.,Cristofanilli Massimo,Alvarez Ricardo H.,Fehn Karen,Fineberg Susan,Sparano Joseph A.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology

Reference41 articles.

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3. Smith CA, Pollice AA, Gu LP et al (2000) Correlations among p53, Her-2/neu, and ras overexpression and aneuploidy by multiparameter flow cytometry in human breast cancer: evidence for a common phenotypic evolutionary pattern in infiltrating ductal carcinomas. Clin Cancer Res 6:112–126

4. Bunone G, Briand PA, Miksicek RJ et al (1996) Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO J 15:2174–2183

5. Kato S, Masuhiro Y, Watanabe M et al (2000) Molecular mechanism of a cross-talk between oestrogen and growth factor signalling pathways. Genes Cells 5:593–601

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