Encapsulation of Leflunomide (LFD) in a novel niosomal formulation facilitated its delivery to THP-1 monocytic cells and enhanced Aryl hydrocarbon receptor (AhR) nuclear translocation and activation-Reference-Cited by-同舟云学术

Encapsulation of Leflunomide (LFD) in a novel niosomal formulation facilitated its delivery to THP-1 monocytic cells and enhanced Aryl hydrocarbon receptor (AhR) nuclear translocation and activation

Published:2019-08-20 Issue:2 Volume:27 Page:635-644
ISSN:2008-2231
Container-title:DARU Journal of Pharmaceutical Sciences
language:en
Short-container-title:DARU J Pharm Sci

Author:

Hasani Mahsa,Sani Neda Abbaspour,Khodabakhshi Behnaz,Arabi Mehdi Sheikh,Mohammadi Saeed,Yazdani Yaghoub

Funder

Golestan University of Medical Sciences

Publisher

Springer Science and Business Media LLC

Subject

Applied Mathematics,General Mathematics

Link

http://link.springer.com/content/pdf/10.1007/s40199-019-00293-0.pdf

Reference34 articles.

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3. Cutolo M, Sulli A, Ghiorzo P, Pizzorni C, Craviotto C, Villaggio B. Anti-inflammatory effects of leflunomide on cultured synovial macrophages from patients with rheumatoid arthritis. Ann Rheum Dis. 2003;62(4):297–302.

4. O'Donnell EF, Saili KS, Koch DC, Kopparapu PR, Farrer D, Bisson WH, et al. The anti-inflammatory drug leflunomide is an agonist of the aryl hydrocarbon receptor. PLoS One. 2010;5(10):e13128.

5. Baban B, Liu JY, Mozaffari MS. Aryl hydrocarbon receptor agonist, leflunomide, protects the ischemic-reperfused kidney: role of Tregs and stem cells. Am J Physiol Regul Integr Comp Physiol. 2012;303(11):R1136–R46.

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