Leflunomide and teriflunomide: altering the metabolism of pyrimidines for the treatment of autoimmune diseases
Author:
Publisher
Informa UK Limited
Subject
Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1586/17512433.2015.1019343
Reference42 articles.
1. Leflunomide Inhibits Pyrimidine de Novo Synthesis in Mitogen-stimulated T-lymphocytes from Healthy Humans
2. The immunomodulatory drug Leflunomide inhibits cell cycle progression of B-CLL cells
3. Leflunomide: mode of action in the treatment of rheumatoid arthritis
4. Disruption of the interaction of T cells with antigen-presenting cells by the active leflunomide metabolite teriflunomide: Involvement of impaired integrin activation and immunologic synapse formation
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