Author:
,NAKONECHNA O. A.,PROKOPYUK V. Y., ,SYDORENKO О. S., ,HOIDINA V. S., ,YANKOVSKA D. O.,
Abstract
The article analyzes the effect of different concentrations of GdYVO4 :Eu3+ nanoparticles solution, which were pre-activated by ultraviolet light and not activated, on metabolic activity of the MCF-7 cancer cell culture. It was found that the degree of changes in the state of breast cancer cells depended on the concentration of nanoparticles, namely, the toxic effect was observed under conditions of exposure to high concentrations.
Publisher
Danylo Halytskyi Lviv National Medical University
Reference10 articles.
1. 1. Chistyakova E. Ye., Smolenko N. P., Belkina I. O., Korenyeva Ye. M., Karpenko N. O. EFFECT OF THE DIFFERENT DOSES OF NANOPARTICLES GADOLINIUM ORTOVANADAT ON THE REPRODUCTIVE FUNCTION OF MALE RATS. Bulletin of problems biology and medicine . 2017. Issue 3 Part 2 (138). 127-129.
2. 2. Onishchenko A., Myasoedov V., Yefimova S., Nakonechna О., Prokopyuk V., Butov D., et all. UV Light-Activated GdYVO4 :Eu3+ Nanoparticles Induce Reactive Oxygen Species Generationin Leukocytes Without Afecting Erythrocytes In Vitro. Biological Trace Element Research, 13 Aug 2021, 200(6): 2777-2792.
3. 3. Maksimchuk P.O, Hubenko K.O, Seminko V.V, Karbivskii V.L, Tkachenko A.S, et all. High antioxidant activity of gadolinium-yttrium orthovanadate nanoparticles in cell-free and biological milieu. Nanotechnology. 2021 Nov 8;33(5).
4. 4. Goltsev A., Babenko N., Gaevska Y., Bondarovych M., Dubrava T., Ostankova L., et all. Toxicity of Nanocomplexes Containing Gadolinium Orthovanadate Nanoparticles and Cholesterol. Biol Trace Elem Res. 2022 Oct; 200(10):4339-4354
5. Mitochondrial potential (ΔΨm) changes in single rat hepatocytes: the effect of orthovanadate nanoparticles doped with rare-earth elements;N.S;Eur Phys J E Soft Matter,2014