The α-Cell Conundrum: ATP-Sensitive K+ Channels and Glucose Sensing
Author:
Affiliation:
1. From the Department of Medicine, Section of Endocrinology, Diabetes and Metabolism, The University of Chicago, Chicago, Illinois
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://journals.org/diabetes/diabetes/article-pdf/58/2/304/507251/zdb00209000304.pdf
Reference19 articles.
1. Unger RH, Aguilar-Parada E, Müller WA, Eisentraut AM: Studies of pancreatic alpha cell function in normal and diabetic subjects. J Clin Invest 49:837–848,1970
2. Gromada J, Franklin I, Wollheim CB: Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains. Endocr Rev 28:84–116,2007
3. Maruyama H, Hisatomi A, Orci L, Grodsky GM, Unger RH: Insulin within islets is a physiologic glucagon release inhibitor. J Clin Invest 74:2296–2299,1984
4. Greenbaum CJ, Havel PJ, Taborsky GJ Jr, Klaff LJ: Intra-islet insulin permits glucose to directly suppress pancreatic A cell function. J Clin Invest 88:767–773,1991
5. Ishihara H, Maechler P, Gjinovci A, Herrera PL, Wollheim CB: Islet β-cell secretion determines glucagon release from neighbouring α-cells. Nat Cell Biol 5:330–335,2003
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