PTEN Expression Contributes to the Regulation of Muscle Protein Degradation in Diabetes
Author:
Affiliation:
1. Nephrology Division, Baylor College of Medicine, Houston, Texas
2. Renal Division, Emory University School of Medicine, Atlanta, Georgia
3. Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana
Abstract
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://journals.org/diabetes/diabetes/article-pdf/56/10/2449/385839/zdb01007002449.pdf
Reference34 articles.
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2. Price SR, Bailey JL, Wang X, Jurkovitz C, England BK, Ding X, Phillips LS, Mitch WE: Muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin-proteasome pathway by a mechanism including gene transcription. J Clin Invest 98:1703–1708,1996
3. Wang XH, Hu Z, Hu JP, Du J, Mitch WE: Insulin resistance accelerates muscle protein degradation: activation of the ubiquitin-proteasome pathway by defects in muscle cell signaling. Endocrinology 147:4160–4168,2006
4. Mitch WE, Goldberg AL: Mechanisms of muscle wasting: the role of the ubiquitin-proteasome system. N Engl J Med 335:1897–1905,1996
5. Lecker SH, Goldberg AL, Mitch WE: Protein degradation by the ubiquitin-proteasome pathway in normal and disease states. J Am Soc Nephrol 17:1807–1819,2006
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