Induction of Tolerance in Type 1 Diabetes via Both CD4+CD25+ T Regulatory Cells and T Regulatory Type 1 Cells
Author:
Affiliation:
1. San Raffaele Scientific Institute, Telethon Institute for Gene Therapy (HSR-TIGET), Milan, Italy
2. San Raffaele Scientific Institute, Diabetes and Endocrinology Unit, Milan, Italy
3. Università Vita-Salute San Raffaele, Milan, Italy
Abstract
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://journals.org/diabetes/diabetes/article-pdf/55/6/1571/660749/zdb00606001571.pdf
Reference43 articles.
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2. Kahan BD, Camardo JS: Rapamycin: clinical results and future opportunities. Transplantation 72: 1181–1193,2001
3. Sehgal SN: Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression. Clin Biochem 31: 335–340,1998
4. Roncarolo MG, Bacchetta R, Bordignon C, Narula S, Levings MK: Type 1 T regulatory cells. Immunol Rev 182: 68–79,2001
5. Shevach EM: CD4+ CD25+ suppressor T cells: more questions than answers. Nat Rev Immunol 2: 389–400,2002
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