Peripheral Proinsulin Expression Controls Low-Avidity Proinsulin-Reactive CD8 T Cells in Type 1 Diabetes
Author:
Affiliation:
1. Diabetes Research Group, Division of Infection and Immunity, Cardiff University School of Medicine, Cardiff University, Cardiff, U.K.
2. Section of Endocrinology, Yale School of Medicine, New Haven, CT
Abstract
Funder
Medical Research Council
JDRF
Diabetes UK Studentship
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://journals.org/diabetes/diabetes/article-pdf/65/11/3429/417915/db151649.pdf
Reference42 articles.
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3. Analysis of antigen specific T cells in diabetes - Lessons from pre-clinical studies and early clinical trials;Krishnamurthy;J Autoimmun,2016
4. Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self;Derbinski;Nat Immunol,2001
5. Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels;Derbinski;J Exp Med,2005
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