2022年度中国神经外科领域高价值论文TOP100
以往我们对一篇论文的价值评估，是通过期刊影响因子或被引频次来判断，这种采用单一指标评判论文的学术价值因有失偏颇而广受诟病。北京同舟云网络信息技术有限公司创立了一种优选算法，综合考虑Metrics 期刊评分、论文被引频次、文献类型以及论文发表时间等多种因素，对每篇论文进行深度解析与计算，并赋予分值，以量化每篇论文的学术价值和影响力。本推荐表是在系统全面准确地统计中国机构作者发表的神经外科领域国际论文的基础上（说明神经外科领域专家为主要完成人发表的全部论文均入选，不再筛选论文的内容主题），对每篇论文依上述方法进行计算并赋分排名而得出的，供相关学者学习、评判、参考和借鉴。
序号 | 年份 | 标题 | 期刊 | 主要完成人 | 论文评分 | 1 | 2022 | Trial of Thrombectomy 6 to 24 Hours after Stroke Due to Basilar-Artery Occlusion | NEW ENGL J MED | 吉训明,首都医科大学,宣武医院,神经外科; | 119508.98 | 2 | 2022 | Effect of Stenting Plus Medical Therapy vs Medical Therapy Alone on Risk of Stroke and Death in Patients With Symptomatic Intracranial Stenosis The CASSISS Randomized Clinical Trial | JAMA-J AM MED ASSOC | 焦力群,首都医科大学,宣武医院,神经外科; | 103005.23 | 3 | 2022 | Olfactory sensory experience regulates gliomagenesis via neuronal IGF1 | NATURE | 刘冲,浙江大学,神经科学研究所; | 35492.12 | 4 | 2022 | Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection | CHEM SOC REV | 张建民,浙江大学,附属第二医院,神经外科; | 28692.93 | 5 | 2022 | Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis | CELL RES | 杨巍,浙江大学,基础医学院; | 20908.87 | 6 | 2022 | A distinct D1-MSN subpopulation down-regulates dopamine to promote negative emotional state | CELL RES | 刘星,复旦大学上海医学院,基础医学院; | 20308.87 | 7 | 2022 | Integrated proteogenomic characterization across major histological types of pituitary neuroendocrine tumors | CELL RES | 赵曜,复旦大学上海医学院,华山医院,神经外科; | 20068.87 | 8 | 2022 | Exploration and functionalization of M1-macrophage extracellular vesicles for effective accumulation in glioblastoma and strong synergistic therapeutic effects | SIGNAL TRANSDUCT TAR | 李维平,深圳市第二人民医院,神经外科; | 16466.58 | 9 | 2022 | EPHA2 mediates PDGFA activity and functions together with PDGFRA as prognostic marker and therapeutic target in glioblastoma | SIGNAL TRANSDUCT TAR | 吕胜青,陆军军医大学,新桥医院,神经外科; | 16466.58 | 10 | 2022 | Natural Coevolution of Tumor and Immunoenvironment in Glioblastoma | CANCER DISCOV | 江涛,首都医科大学,北京天坛医院,神经外科; | 16086.64 | 11 | 2022 | Achieving Efficient NIR-II Type-I Photosensitizers for Photodynamic/Photothermal Therapy upon Regulating Chalcogen Elements | ADV MATER | 蔡晓东,深圳大学,第二人民医院,神经外科; | 15954.94 | 12 | 2022 | Nanosensitizers for sonodynamic therapy for glioblastoma multiforme: current progress and future perspectives | MILITARY MED RES | 程宏伟,安徽医科大学,第一附属医院,神经外科; | 14294.01 | 13 | 2022 | Neisseria meningitidis Opca Protein/MnO2 Hybrid Nanoparticles for Overcoming the Blood-Brain Barrier to Treat Glioblastoma | ADV MATER | 徐建国,四川大学,华西医院,神经外科; | 14034.94 | 14 | 2022 | Intracellular accumulation of tau inhibits autophagosome formation by activating TIA1-amino acid-mTORC1 signaling | MILITARY MED RES | 李俊,华中科技大学,附属武汉市中心医院,神经外科; | 13694.01 | 15 | 2022 | Spleen-Targeted Glabridin-Loaded Nanoparticles Regulate Polarization of Monocyte/Macrophage (M-o/M-phi) for the Treatment of Cerebral Ischemia-Reperfusion Injury | ADV MATER | 祝新根,南昌大学,第二附属医院,神经外科; | 12234.94 | 16 | 2022 | Transmembrane water-efflux rate measured by magnetic resonance imaging as a biomarker of the expression of aquaporin-4 in gliomas | NAT BIOMED ENG | 刘英超,山东大学,附属省立医院,神经外科; | 10926.84 | 17 | 2022 | The Prevalence and Treatment of Diabetes in China From 2013 to 2018 | JAMA-J AM MED ASSOC | 涂文军,首都医科大学,附属北京天坛医院,神经外科; | 10216.52 | 18 | 2022 | Glioma targeted therapy: insight into future of molecular approaches | MOL CANCER | 程全,中南大学,湘雅医院,神经外科; | 9552.10 | 19 | 2022 | Machine learning-based tumor-infiltrating immune cell-associated lncRNAs for predicting prognosis and immunotherapy response in patients with glioblastoma | BRIEF BIOINFORM | 程全,中南大学,湘雅医院,神经外科; | 8958.56 | 20 | 2022 | Distinct spatiotemporal patterns of syntactic and semantic processing in human inferior frontal gyrus | NAT HUM BEHAV | 吴劲松,复旦大学上海医学院,华山医院,神经外科; | 8543.86 | 21 | 2022 | Localized NIR-II laser mediated chemodynamic therapy of glioblastoma | NANO TODAY | 张建民,浙江大学,附属第二医院,神经外科; | 8150.04 | 22 | 2022 | Hybrid nanogenerator based closed-loop self-powered low-level vagus nerve stimulation system for atrial fibrillation treatment | SCI BULL | 毛更生,武警总医院,神经血管外科; | 7846.39 | 23 | 2022 | SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy | J MED VIROL | 王培会,山东大学,高等医学研究院; | 7777.30 | 24 | 2022 | Binaural processing deficit and cognitive impairment in Alzheimer's disease | ALZHEIMERS DEMENT | 赵国光,首都医科大学,宣武医院,神经外科; | 7203.45 | 25 | 2022 | Immunostimulant In Situ Hydrogel Improves Synergetic Radioimmunotherapy of Malignant Glioblastoma Relapse Post-Resection | ADV FUNCT MATER | 季晶,南京医科大学,第一附属医院,神经外科; | 6721.62 | 26 | 2022 | Hesperetin Nanoparticle Targeting Neutrophils for Enhanced TBI Therapy | ADV FUNCT MATER | 张相彤,哈尔滨医科大学,附属第一医院,神经外科; | 6601.62 | 27 | 2022 | CpG island reconfiguration for the establishment and synchronization of polycomb functions upon exit from naive pluripotency | MOL CELL | 吴旭东,天津医科大学,基础医学院; | 6584.39 | 28 | 2022 | Recombinant human collagen hydrogels with hierarchically ordered microstructures for corneal stroma regeneration | CHEM ENG J | 谭回,深圳大学附属第一医院; | 6580.36 | 29 | 2022 | An Intelligent Nanoplatform for Orthotopic Glioblastoma Therapy by Nonferrous Ferroptosis | ADV FUNCT MATER | 赵刚,吉林大学,第一医院,神经外科; | 6481.62 | 30 | 2022 | Upregulated YB-1 protein promotes glioblastoma growth through a YB-1/CCT4/mLST8/mTOR pathway | J CLIN INVEST | 杨柳松,复旦大学上海医学院,华山医院,神经外科; | 6399.42 | 31 | 2022 | Ultrasound-driven in vivo electrical stimulation based on biodegradable piezoelectric nanogenerators for enhancing and monitoring the nerve tissue repair | NANO ENERGY | 蒋伟,华中科技大学,附属同济医院,神经外科; | 6353.43 | 32 | 2022 | Mutual promotion of oxidative stress amplification and calcium overload by degradable spatially selective self-cascade catalyst for synergistic tumor therapy | CHEM ENG J | 万志平,同济大学,同济医院,神经外科; | 6340.36 | 33 | 2022 | Sec13 promotes oligodendrocyte differentiation and myelin repair through autocrine pleiotrophin signaling | J CLIN INVEST | 王占祥,厦门大学,附属第一医院,神经外科; | 6279.42 | 34 | 2022 | Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas | MOL CELL | 尤永平,南京医科大学,第一附属医院,神经外科; | 6224.39 | 35 | 2022 | Exosomal miR-101-3p and miR-423-5p inhibit medulloblastoma tumorigenesis through targeting FOXP4 and EZH2 | CELL DEATH DIFFER | 李昊,复旦大学上海医学院,儿科医院,神经外科; | 6208.88 | 36 | 2022 | Osteoimmunomodulatory injectable Lithium-Heparin hydrogel with Microspheres/TGF-beta 1 delivery promotes M2 macrophage polarization and osteogenesis for guided bone regeneration | CHEM ENG J | 田猛,四川大学,华西医院,神经外科; | 6100.36 | 37 | 2022 | Two predominant molecular subtypes of spinal meningioma: thoracic NF2-mutant tumors strongly associated with female sex, and cervical AKT1-mutant tumors originating ventral to the spinal cord | ACTA NEUROPATHOL | 华领洋,复旦大学上海医学院,华山医院,神经外科; | 5973.88 | 38 | 2022 | Biomimetic Yolk-Shell Nanocatalysts for Activatable Dual-Modal-Image-Guided Triple- Augmented Chemodynamic Therapy of Cancer | ACS NANO | 张建民,浙江大学,附属第二医院,神经外科; | 5912.13 | 39 | 2022 | DNA Origami as a Nanomedicine for Targeted Rheumatoid Arthritis Therapy through Reactive Oxygen Species and Nitric Oxide Scavenging | ACS NANO | 董军,苏州大学,附属第二医院,神经外科; | 5792.13 | 40 | 2022 | Ferroptosis, as the most enriched programmed cell death process in glioma, induces immunosuppression and immunotherapy resistance | NEURO-ONCOLOGY | 吴安华,中国医科大学,附属第一医院,神经外科; | 5719.00 | 41 | 2022 | Delivery of miRNAs through Metal-Organic Framework Nanoparticles for Assisting Neural Stem Cell Therapy for Ischemic Stroke | ACS NANO | 辛涛,山东大学,附属省立医院,神经外科; | 5672.13 | 42 | 2022 | Inducible Pluripotent Stem Cell-Derived Small Extracellular Vesicles Rejuvenate Senescent Blood-Brain Barrier to Protect against Ischemic Stroke in Aged Mice | ACS NANO | 邓志锋,上海交通大学医学院,第六人民医院,神经外科; | 5672.13 | 43 | 2022 | Intrinsic carbon defects induced nickel phosphate/carbon photocatalyst for high performance bacterial disinfection | CHEM ENG J | 杨大鹏,泉州师范学院; | 5620.36 | 44 | 2022 | Optimizing the electronic structure of BiOBr via constructing oxygen-rich vacancies for highly efficient NIR light-driven antibacterial activity | CHEM ENG J | 李耀华,天津医科大学总医院,神经外科; | 5620.36 | 45 | 2022 | An MRI radiomics approach to predict survival and tumour-infiltrating macrophages in gliomas | BRAIN | 张伟,首都医科大学,附属北京天坛医院,神经外科; | 5620.09 | 46 | 2022 | Long non-coding RNAs as epigenetic mediator and predictor of glioma progression, invasiveness, and prognosis | SEMIN CANCER BIOL | 侯坤,吉林大学,白求恩第一医院,二部神经外科; | 5610.35 | 47 | 2022 | The microbiota-gut-brain axis participates in chronic cerebral hypoperfusion by disrupting the metabolism of short-chain fatty acids | MICROBIOME | 顾宇翔,复旦大学上海医学院,华山医院,神经外科; | 5538.46 | 48 | 2022 | Gestational diabetes mellitus and adverse pregnancy outcomes: systematic review and meta-analysis | BMJ-BRIT MED J | 刘方琨,中南大学,湘雅医院,神经外科; | 5524.94 | 49 | 2022 | Antiepilepticus Effects of Tetrahedral Framework Nucleic Acid via Inhibition of Gliosis-Induced Downregulation of Glutamine Synthetase and Increased AMPAR Internalization in the Postsynaptic Membrane | NANO LETT | 徐如祥,解放军总医院第七医学中心,神经外科; | 5284.04 | 50 | 2022 | Dual-function hydrogels with sequential release of GSK3 beta inhibitor and VEGF inhibit inflammation and promote angiogenesis after stroke | CHEM ENG J | 徐建国,四川大学,华西医院,神经外科; | 5260.36 | 51 | 2022 | A clinically relevant model of focal embolic cerebral ischemia by thrombus and thrombolysis in rhesus monkeys | NAT PROTOC | 吉训明,首都医科大学,宣武医院,神经外科; | 5254.06 | 52 | 2022 | alpha-Synuclein as a Target for Metallo-Anti-Neurodegenerative Agents | ANGEW CHEM INT EDIT | 刘扬中,中国科学技术大学; | 5172.72 | 53 | 2022 | A BRD4 PROTAC nanodrug for glioma therapy via the intervention of tumor cells proliferation, apoptosis and M2 macrophages polarization | ACTA PHARM SIN B | 高祥,四川大学,华西医院,神经外科; | 5120.95 | 54 | 2022 | The efficacy and safety of dual orexin receptor antagonists in primary insomnia: A systematic review and network meta-analysis | SLEEP MED REV | 王中,苏州大学,附属第一医院,神经外科; | 5074.33 | 55 | 2022 | Cortical phase-amplitude coupling is key to the occurrence and treatment of freezing of gait | BRAIN | 张建国,首都医科大学,北京天坛医院,神经外科; | 5020.09 | 56 | 2022 | IKBKE phosphorylates and stabilizes Snail to promote breast cancer invasion and metastasis | CELL DEATH DIFFER | 黄强,天津医科大学总医院,神经外科; | 5008.88 | 57 | 2022 | Metabolic reprogramming in astrocytes results in neuronal dysfunction in intellectual disability | MOL PSYCHIATR | 王鑫,厦门大学,生命科学学院; | 4954.87 | 58 | 2022 | A novel circular RNA, circIgfbp2, links neural plasticity and anxiety through targeting mitochondrial dysfunction and oxidative stress-induced synapse dysfunction after traumatic brain injury | MOL PSYCHIATR | 廖正步,重庆医科大学,附属第一医院,神经外科; | 4954.87 | 59 | 2022 | C/EBP beta/AEP signaling couples atherosclerosis to the pathogenesis of Alzheimer's disease | MOL PSYCHIATR | 陈谦学,武汉大学,人民医院,神经外科; | 4954.87 | 60 | 2022 | Subdural neural interfaces for long-term electrical recording, optical microscopy and magnetic resonance imaging | BIOMATERIALS | 汪浩,浙江大学,神经科学研究所; | 4919.54 | 61 | 2022 | NCOR1 maintains the homeostasis of vascular smooth muscle cells and protects against aortic aneurysm | CELL DEATH DIFFER | 贾锋,上海交通大学医学院,附属仁济医院;神经外科; | 4888.88 | 62 | 2022 | N-6-Methyladenosine-modified lncRNA LINREP promotes Glioblastoma progression by recruiting the PTBP1/HuR complex | CELL DEATH DIFFER | 辛涛,山东大学,附属省立医院,神经外科; | 4888.88 | 63 | 2022 | Neutrophil Extracellular Traps may be a Potential Target for Treating Early Brain Injury in Subarachnoid Hemorrhage | TRANSL STROKE RES | 陈高,浙江大学,附属第二医院,神经外科; | 4885.59 | 64 | 2022 | Dual-responsive nanoparticles with transformable shape and reversible charge for amplified chemo-photodynamic therapy of breast cancer | ACTA PHARM SIN B | 高祥,四川大学,华西医院,神经外科; | 4880.95 | 65 | 2022 | A short period of early life oxytocin treatment rescues social behavior dysfunction via suppression of hippocampal hyperactivity in male mice | MOL PSYCHIATR | 汪浩,浙江大学,神经科学研究所; | 4834.87 | 66 | 2022 | Pathological oligodendrocyte precursor cells revealed in human schizophrenic brains and trigger schizophrenia-like behaviors and synaptic defects in genetic animal model | MOL PSYCHIATR | 肖岚,陆军军医大学; | 4834.87 | 67 | 2022 | A causal association of ANKRD37 with human hippocampal volume | MOL PSYCHIATR | 吴旭东,天津医科大学,基础医学院; | 4834.87 | 68 | 2022 | Structural alignment guides oriented migration and differentiation of endogenous neural stem cells for neurogenesis in brain injury treatment | BIOMATERIALS | 张玉琪,北京清华长庚医院,神经外科; | 4799.54 | 69 | 2022 | Modified exosomal SIRP alpha variants alleviate white matter injury after intracerebral hemorrhage via microglia/macrophages | BIOMATER RES | 顾宇翔,复旦大学上海医学院,华山医院,神经外科; | 4782.94 | 70 | 2022 | Basilar Artery Occlusion Chinese Endovascular Trial: Protocol for a prospective randomized controlled study | INT J STROKE | 吉训明,首都医科大学,宣武医院,神经外科; | 4710.97 | 71 | 2022 | Biomarkers used in Alzheimer's disease diagnosis, treatment, and prevention | AGEING RES REV | 冯军,华中科技大学,附属协和医院,神经外科; | 4659.35 | 72 | 2022 | Wnt signaling: A prospective therapeutic target for chronic pain | PHARMACOL THERAPEUT | 叶达伟,华中科技大学,同济医院中法新城院区; | 4659.33 | 73 | 2022 | Circular RNA circBFAR promotes glioblastoma progression by regulating a miR-548b/FoxM1 axis | FASEB J | 梁鹏,哈尔滨医科大学,附属肿瘤医院,神经外科; | 4653.39 | 74 | 2022 | Three-Dimensional-Cultured MSC-Derived Exosome-Hydrogel Hybrid Microneedle Array Patch for Spinal Cord Repair | NANO LETT | 辛涛,山东大学,附属省立医院,神经外科; | 4564.04 | 75 | 2022 | Cerium oxide nanoparticles with antioxidative neurorestoration for ischemic stroke | BIOMATERIALS | 陈罡,苏州大学,附属第一医院,神经外科; | 4559.54 | 76 | 2022 | Interrogating glioma-M2 macrophage interactions identifies Gal-9/Tim-3 as a viable target against PTEN-null glioblastoma | SCI ADV | 陈忠平,中山大学,肿瘤防治中心,神经外科; | 4542.22 | 77 | 2022 | Characteristics, surgical outcomes, and influential factors of epilepsy in Sturge-Weber syndrome | BRAIN | 栾国明,首都医科大学,三博脑科医院,神经外科; | 4540.09 | 78 | 2022 | LncRNA CEBPA-AS1 alleviates cerebral ischemia-reperfusion injury by sponging miR-340-5p regulating APPL1/LKB1/AMPK pathway | FASEB J | 涂献坤,福建医科大学,附属协和医院,神经外科; | 4533.39 | 79 | 2022 | Multifunctional Hollow MnO2@Porphyrin@Bromelain Nanoplatform for Enhanced Photodynamic Therapy | SMALL | 涂献坤,福建医科大学,附属协和医院,神经外科; | 4499.66 | 80 | 2022 | Structural and functional brain alterations in Cushing?s disease: A narrative review | FRONT NEUROENDOCRIN | 冯铭,中国医学科学院,神经外科; | 4439.18 | 81 | 2022 | UCSCXenaShiny: an R/CRAN package for interactive analysis of UCSC Xena data | BIOINFORMATICS | 李学军,中南大学,湘雅医院,神经外科; | 4341.51 | 82 | 2022 | Inhalation of MSC-EVs is a noninvasive strategy for ameliorating acute lung injury | J CONTROL RELEASE | 龙乾发,西安市中心医院,神经外科; | 4302.99 | 83 | 2022 | RNA binding protein NKAP protects glioblastoma cells from ferroptosis by promoting SLC7A11 mRNA splicing in an m(6)A-dependent manner | CELL DEATH DIS | 庞琦,山东大学,山东省立医院,神经外科; | 4277.31 | 84 | 2022 | Interleukins and Ischemic Stroke | FRONT IMMUNOL | 邱晟,湖州市中心医院,神经外科; | 4215.55 | 85 | 2022 | Fast-developing fatal diffuse leptomeningeal dissemination of a pineal germinoma in a young child: a case report and literature review | BRIT J NEUROSURG | 鞠延,四川大学,华西医院,神经外科; | 4183.82 | 86 | 2022 | Fe(III)-Shikonin Supramolecular Nanomedicine for Combined Therapy of Tumor via Ferroptosis and Necroptosis | ADV HEALTHC MATER | 葛鹏飞,吉林大学,附属第一医院,神经外科; | 4168.44 | 87 | 2022 | Loss of FBXW7 Correlates with Increased IDH1 Expression in Glioma and Enhances IDH1-Mutant Cancer Cell Sensitivity to Radiation | CANCER RES | 王新军,郑州大学,第五附属医院,神经外科; | 4145.93 | 88 | 2022 | Locally secreted BiTEs complement CAR T cells by enhancing killing of antigen heterogeneous solid tumors | MOL THER | 林志国,哈尔滨医科大学,附属第一医院,神经外科; | 4114.26 | 89 | 2022 | Negative effects of brain regulatory T cells depletion on epilepsy | PROG NEUROBIOL | 赵冬冬,四川省人民医院,神经外科; | 4112.02 | 90 | 2022 | Clinical significance and molecular annotation of cellular morphometric subtypes in lower-grade gliomas discovered by machine learning | NEURO-ONCOLOGY | 李志强,武汉大学,中南医院,神经外科; | 4039.00 | 91 | 2022 | Machine learning-based identification of tumor-infiltrating immune cell-associated lncRNAs for improving outcomes and immunotherapy responses in patients with low-grade glioma | THERANOSTICS | 程全,中南大学,湘雅医院,神经外科; | 3991.07 | 92 | 2022 | Inhibition of caspase-1-mediated inflammasome activation reduced blood coagulation in cerebrospinal fluid after subarachnoid haemorrhage | EBIOMEDICINE | 陈盛,浙江大学,附属第二医院,神经外科; | 3968.83 | 93 | 2022 | Simultaneous delivery of immune stimulatory gene and checkpoint blocker via targeted nanoparticles to strengthen antitumor immunity | MATER TODAY NANO | 高祥,四川大学,华西医院,神经外科; | 3925.66 | 94 | 2022 | FRK inhibits glioblastoma progression via phosphorylating YAP and inducing its ubiquitylation and degradation by Siah1 | NEURO-ONCOLOGY | 周秀萍,徐州医科大学,附属医院,神经外科; | 3919.00 | 95 | 2022 | USF1/CD90 signaling in maintaining glioblastoma stem cells and tumor-associated macrophages adhesion | NEURO-ONCOLOGY | 付朋,华中科技大学,附属协和医院,神经外科; | 3919.00 | 96 | 2022 | Structural and functional correlates of the response to deep brain stimulation at ventral capsule/ventral striatum region for treatment-resistant depression | J NEUROL NEUROSUR PS | 孙伯民,上海交通大学医学院,瑞金医院,神经外科; | 3916.17 | 97 | 2022 | HSP90-CDC37 functions as a chaperone for the oncogenic FGFR3-TACC3 fusion | MOL THER | 杨学军,天津医科大学总医院,神经外科; | 3874.26 | 98 | 2022 | FOSL1 promotes proneural-to-mesenchymal transition of glioblastoma stem cells via UBC9/CYLD/NF-B-K axis | MOL THER | 王慧博,南京医科大学,第一附属医院,神经外科; | 3874.26 | 99 | 2022 | Safety of Withholding Perioperative Hydrocortisone for Patients With Pituitary Adenomas With an Intact Hypothalamus-Pituitary-Adrenal Axis A Randomized Clinical Trial | JAMA NETW OPEN | 幸兵,中国医学科学院,北京协和医院,神经外科; | 3801.48 | 100 | 2022 | Transcription factor GTF2B regulates AIP protein expression in growth hormone-secreting pituitary adenomas and influences tumor phenotypes | NEURO-ONCOLOGY | 吴群,浙江大学,附属第二医院,神经外科; | 3799.00 |
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