2022年度中国眼科领域高价值论文TOP100
以往我们对一篇论文的价值评估，是通过期刊影响因子或被引频次来判断，这种采用单一指标评判论文的学术价值因有失偏颇而广受诟病。北京同舟云网络信息技术有限公司创立了一种优选算法，综合考虑Metrics 期刊评分、论文被引频次、文献类型以及论文发表时间等多种因素，对每篇论文进行深度解析与计算，并赋予分值，以量化每篇论文的学术价值和影响力。本推荐表是在系统全面准确地统计中国机构作者发表的眼科领域国际论文的基础上（说明眼科领域专家为主要完成人发表的全部论文均入选，不再筛选论文的内容主题），对每篇论文依上述方法进行计算并赋分排名而得出的，供相关学者学习、评判、参考和借鉴。
序号 | 年份 | 标题 | 期刊 | 主要完成人 | 论文评分 | 1 | 2022 | A digital mask to safeguard patient privacy | NAT MED | 林浩添,中山大学,中山眼科中心,眼科; | 46431.08 | 2 | 2022 | Global retinoblastoma survival and globe preservation: a systematic review and meta-analysis of associations with socioeconomic and health-care factors | LANCET GLOB HEALTH | Yam, Jason C.,香港中文大学,Department of Ophthalmology & Visual Sciences; | 17031.27 | 3 | 2022 | Multi-omic characterization of genome-wide abnormal DNA methylation reveals diagnostic and prognostic markers for esophageal squamous-cell carcinoma | SIGNAL TRANSDUCT TAR | 苏建忠,中国科学院大学,温州研究院; | 15866.58 | 4 | 2022 | Extrachromosomal circular DNA: biogenesis, structure, functions and diseases | SIGNAL TRANSDUCT TAR | 庄艾,上海交通大学医学院,第九人民医院,眼科; | 15386.58 | 5 | 2022 | Immunoregulation in Diabetic Wound Repair with a Photoenhanced Glycyrrhizic Acid Hydrogel Scaffold | ADV MATER | 沈建良,温州医科大学,附属眼视光学院; | 14394.94 | 6 | 2022 | Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/beta-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability | MILITARY MED RES | 韩静,空军军医大学,唐都医院,眼科; | 13694.01 | 7 | 2022 | Sulfur-based fluorescent probes for HOCl: Mechanisms, design, and applications | COORDIN CHEM REV | 沈建良,温州医科大学,附属眼视光学院; | 12774.01 | 8 | 2022 | Engineering Hibiscus-Like Riboflavin/ZIF-8 Microsphere Composites to Enhance Transepithelial Corneal Cross-Linking | ADV MATER | 周行涛,复旦大学上海医学院,眼耳鼻喉科医院,眼科; | 12474.94 | 9 | 2022 | Tumor Selective Metabolic Reprogramming as a Prospective PD-L1 Depression Strategy to Reactivate Immunotherapy | ADV MATER | 沈建良,温州医科大学,附属眼视光学院; | 12354.94 | 10 | 2022 | Injectable Anti-Inflammatory Supramolecular Nanofiber Hydrogel to Promote Anti-VEGF Therapy in Age-Related Macular Degeneration Treatment | ADV MATER | 谷平,上海交通大学医学院,第九人民医院,眼科; | 12234.94 | 11 | 2022 | Visualized Gallium/Lyticase-Integrated Antifungal Strategy for Fungal Keratitis Treatment | ADV MATER | 姚克,浙江大学,附属第二医院,眼科; | 12234.94 | 12 | 2022 | Loss of PRMT7 reprograms glycine metabolism to selectively eradicate leukemia stem cells in CML | CELL METAB | 潘景轩,中山大学,中山医学院; | 12233.79 | 13 | 2022 | Diagnostic assessment of glaucoma and non-glaucomatous optic neuropathies via optical texture analysis of the retinal nerve fibre layer | NAT BIOMED ENG | 梁启信,香港中文大学; | 10926.84 | 14 | 2022 | Single-cell transcriptomics of adult macaque hippocampus reveals neural precursor cell populations | NAT NEUROSCI | 刘奕志,中山大学,中山眼科中心,眼科; | 10819.24 | 15 | 2022 | Diet-induced inflammation in the anterior paraventricular thalamus induces compulsive sucrose-seeking | NAT NEUROSCI | 周煜东,浙江大学,医学院基础医学系; | 10579.24 | 16 | 2022 | Effect of Text Messaging Parents of School-Aged Children on Outdoor Time to Control Myopia A Randomized Clinical Trial | JAMA PEDIATR | 王宁利,首都医科大学,北京同仁医院,青光眼科; | 9622.20 | 17 | 2022 | Multiomics integration-based molecular characterizations of COVID-19 | BRIEF BIOINFORM | 周猛,温州医科大学,眼视光学院; | 9558.56 | 18 | 2022 | Recent advances of luminescent sensors for iron and copper: Platforms, mechanisms, and bio-applications | COORDIN CHEM REV | 沈建良,温州医科大学,附属眼视光学院; | 9294.01 | 19 | 2022 | Deep learning-based advances and applications for single-cell RNA-sequencing data analysis | BRIEF BIOINFORM | 瞿佳,温州医科大学,附属眼视光医院,眼科; | 8958.56 | 20 | 2022 | RiboChat: a chat-style web interface for analysis and annotation of ribosome profiling data | BRIEF BIOINFORM | 谢志,中山大学,中山眼科中心,国家重点实验室; | 8478.56 | 21 | 2022 | Bacteria-Targeting Photodynamic Nanoassemblies for Efficient Treatment of Multidrug-Resistant Biofilm Infected Keratitis | ADV FUNCT MATER | 睢瑞芳,中国医学科学院,北京协和医院,眼科; | 8041.62 | 22 | 2022 | Regulation of epigenetic homeostasis in uveal melanoma and retinoblastoma | PROG RETIN EYE RES | 范先群,上海交通大学医学院,医学院本部; | 7880.03 | 23 | 2022 | NIR-II Photo-Amplified Sonodynamic Therapy Using Sodium Molybdenum Bronze Nanoplatform against Subcutaneous Staphylococcus Aureus Infection | ADV FUNCT MATER | 沈建良,温州医科大学,附属眼视光学院; | 7801.62 | 24 | 2022 | The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas | PROG RETIN EYE RES | 谢立信,山东第一医科大学,山东省眼科医院,眼科; | 7520.03 | 25 | 2022 | Bacteroides ovatus-mediated CD27(-) MAIT cell activation is associated with obesity-related T2D progression | CELL MOL IMMUNOL | 魏来,中山大学,眼科中心,眼内微生物组与眼免疫; | 7440.45 | 26 | 2022 | Multimodal oncolytic bacteria by coating with tumor cell derived nanoshells | NANO TODAY | 庞燕,上海交通大学医学院,第九人民医院,眼科; | 7430.04 | 27 | 2022 | Multifunctional Supramolecular Filament Hydrogel Boosts Anti-Inflammatory Efficacy In Vitro and In Vivo | ADV FUNCT MATER | 李星熠,温州医科大学,附属眼视光医院; | 7081.62 | 28 | 2022 | GABA(A)(delta) receptor hypofunction in the amygdala-hippocampal circuit underlies stress-induced anxiety | SCI BULL | 潘秉兴,南昌大学,生命科学研究院; | 7006.39 | 29 | 2022 | Air-permeable electrode for highly sensitive and noninvasive glucose monitoring enabled by graphene fiber fabrics | NANO ENERGY | 王毅,温州医科大学,生物技术与工程学院; | 6953.43 | 30 | 2022 | Simultaneously deplete reactive oxygen species and inhibit pyroptosis by dopamine/thioketal-containing polymers delivering disulfiram in combination with Cu(II) for acute glaucoma | NANO TODAY | 周学智,中南大学,湘雅医院,眼科; | 6830.04 | 31 | 2022 | A cascade FRET photosensitizer that enhances photodynamic therapy for ocular melanoma | NANO TODAY | 葛盛芳,上海交通大学医学院,第九人民医院,眼科; | 6830.04 | 32 | 2022 | Long-term corneal recovery by simultaneous delivery of hPSC-derived corneal endothelial precursors and nicotinamide | J CLIN INVEST | 史伟云,山东省眼科医院,眼科; | 6759.42 | 33 | 2022 | Continuous Self-Oxygenated Double-Layered Hydrogel under Natural Light for Real-Time Infection Monitoring, Enhanced Photodynamic Therapy, and Hypoxia Relief in Refractory Diabetic Wounds Healing | ADV FUNCT MATER | 王佰亮,温州医科大学,附属眼视光医院,眼科; | 6601.62 | 34 | 2022 | Targeting C3b/C4b and VEGF with a bispecific fusion protein optimized for neovascular age-related macular degeneration therapy | SCI TRANSL MED | 孙晓东,上海交通大学医学院,第一人民医院; | 6580.53 | 35 | 2022 | All-in-one: Harnessing multifunctional injectable natural hydrogels for ordered therapy of bacteria-infected diabetic wounds | CHEM ENG J | 沈建良,温州医科大学,附属眼视光学院; | 6580.36 | 36 | 2022 | Shear stress-induced cellular senescence blunts liver regeneration through Notch-sirtuin 1-P21/P16 axis | HEPATOLOGY | 窦国睿,空军军医大学,西京医院,眼科; | 6500.99 | 37 | 2022 | Multimodal deep learning with feature level fusion for identification of choroidal neovascularization activity in age-related macular degeneration | ACTA OPHTHALMOL | 叶娟,浙江大学,医学院; | 6398.91 | 38 | 2022 | Exosomes-loaded thermosensitive hydrogels for corneal epithelium and stroma regeneration | BIOMATERIALS | 姚克,浙江大学,附属第二医院,眼科; | 6359.54 | 39 | 2022 | A deep-learning system predicts glaucoma incidence and progression using retinal photographs | J CLIN INVEST | 张秀兰,中山大学,中山眼科中心,眼科; | 6279.42 | 40 | 2022 | Integrating convolution and self-attention improves language model of human genome for interpreting non-coding regions at base-resolution | NUCLEIC ACIDS RES | 吴继红,复旦大学上海医学院,眼耳鼻喉科医院,上海市视觉损害与重建重点实验室; | 6272.36 | 41 | 2022 | Deficiency of ribosomal proteins reshapes the transcriptional and translational landscape in human cells | NUCLEIC ACIDS RES | 谢志,中山大学,中山眼科中心,国家重点实验室; | 6272.36 | 42 | 2022 | PncsHub: a platform for annotating and analyzing non-classically secreted proteins in Gram-positive bacteria | NUCLEIC ACIDS RES | 苏建忠,中国科学院大学,温州研究院; | 6272.36 | 43 | 2022 | Mechanistic insight into allosteric activation of human pyruvate carboxylase by acetyl-CoA | MOL CELL | 范先群,上海交通大学医学院,医学院本部; | 6224.39 | 44 | 2022 | Cascade catalytic platform modified intraocular lens for high-efficient posterior capsule opacification prevention | CHEM ENG J | 林全愧,温州医科大学,附属眼视光医院,眼科; | 6220.36 | 45 | 2022 | Sequential drug release of co-assembled supramolecular hydrogel as synergistic therapy against Staphylococcus aureus endophthalmitis | CHEM ENG J | 李星熠,温州医科大学,附属眼视光医院; | 6100.36 | 46 | 2022 | Instant Adhesion of Amyloid-like Nanofilms with Wet Surfaces | ACS CENTRAL SCI | 王佰亮,温州医科大学,附属眼视光医院,眼科; | 6088.10 | 47 | 2022 | Three-Year Clinical Trial of Low-Concentration Atropine for Myopia Progression (LAMP) Study: Continued Versus Washout Phase 3 Report | OPHTHALMOLOGY | Yam, Jason C.,香港中文大学,Department of Ophthalmology & Visual Sciences; | 6076.21 | 48 | 2022 | HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway | AUTOPHAGY | 张学东,重庆医科大学,第一临床学院,眼科; | 6044.55 | 49 | 2022 | Photo-responsive intraocular lens with on demand drug release for posterior capsule opacification prevention and improved biosafety | CHEM ENG J | 林全愧,温州医科大学,附属眼视光医院,眼科; | 5980.36 | 50 | 2022 | A PEDOT:PSS conductive hydrogel incorporated with Prussian blue nanoparticles for wearable and noninvasive monitoring of glucose | CHEM ENG J | 王毅,温州医科大学,生物技术与工程学院; | 5980.36 | 51 | 2022 | pH-Activatable Organic Nanoparticles for Efficient Low-Temperature Photothermal Therapy of Ocular Bacterial Infection | ACS NANO | 王佰亮,温州医科大学,附属眼视光医院,眼科; | 5912.13 | 52 | 2022 | Notch-triggered maladaptation of liver sinusoidal endothelium aggravates nonalcoholic steatohepatitis through endothelial nitric oxide synthase | HEPATOLOGY | 窦国睿,空军军医大学,西京医院,眼科; | 5900.99 | 53 | 2022 | Effect of Repeated Low-Level Red-Light Therapy for Myopia Control in Children A Multicenter Randomized Controlled Trial | OPHTHALMOLOGY | 何明光,中山大学,中山眼科中心,激光近视眼治疗中心; | 5836.21 | 54 | 2022 | A Rapid Corneal Healing Microneedle for Efficient Ocular Drug Delivery | SMALL | 李星熠,温州医科大学,附属眼视光医院; | 5819.66 | 55 | 2022 | Discovering the Secret of Diseases by Incorporated Tear Exosomes Analysis via Rapid-Isolation System: iTEARS | ACS NANO | 刘飞,温州医科大学,附属眼视光学院; | 5792.13 | 56 | 2022 | Targeting Cell Membranes, Depleting ROS by Dithiane and Thioketal-Containing Polymers with Pendant Cholesterols Delivering Necrostatin-1 for Glaucoma Treatment | ACS NANO | 夏晓波,中南大学,湘雅医院,眼科; | 5672.13 | 57 | 2022 | Cell Wall Destruction and Internal Cascade Synergistic Antifungal Strategy for Fungal Keratitis | ACS NANO | 姚克,浙江大学,附属第二医院,眼科; | 5672.13 | 58 | 2022 | Nacre-inspired underwater superoleophobic films with high transparency and mechanica robustness | NAT PROTOC | 王佰亮,温州医科大学,附属眼视光医院,眼科; | 5614.06 | 59 | 2022 | Multimodal Machine Learning Using Visual Fields and Peripapillary Circular OCT Scans in Detection of Glaucomatous Optic Neuropathy | OPHTHALMOLOGY | 张秀兰,中山大学,中山眼科中心,眼科; | 5596.21 | 60 | 2022 | A biolayer interferometry-based, aptamer-antibody receptor pair biosensor for real-time, sensitive, and specific detection of the disease biomarker TNF-alpha | CHEM ENG J | 吴继红,复旦大学上海医学院,眼耳鼻喉科医院,上海市视觉损害与重建重点实验室; | 5380.36 | 61 | 2022 | Inhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration | CELL DEATH DIFFER | 李万程,中山大学,眼科学国家重点实验室 ; | 5368.88 | 62 | 2022 | UV-assisted ultrafast construction of robust Fe3O4/polydopamine/Ag Fenton-like catalysts for highly efficient micropollutant decomposition | SCI TOTAL ENVIRON | 齐晓亮,温州医科大学,眼科视觉科学国家重点实验室; | 5368.09 | 63 | 2022 | Dendritic Hydrogels with Robust Inherent Antibacterial Properties for Promoting Bacteria-Infected Wound Healing | ACS APPL MATER INTER | 齐晓亮,温州医科大学,眼科视觉科学国家重点实验室; | 5358.18 | 64 | 2022 | Ruthenium-Based Metal-Organic Nanoradiosensitizers Enhance Radiotherapy by Combining ROS Generation and CO Gas Release | ANGEW CHEM INT EDIT | 楚成超,厦门大学,眼科研究所; | 5292.72 | 65 | 2022 | A Separation-Sensing Platform Performing Accurate Diagnosis of Jaundice in Complex Biological Tear Fluids | ANGEW CHEM INT EDIT | 冯云,北京大学,第三医院,眼科; | 5292.72 | 66 | 2022 | Pathologically high intraocular pressure disturbs normal iron homeostasis and leads to retinal ganglion cell ferroptosis in glaucoma | CELL DEATH DIFFER | 夏晓波,中南大学,湘雅医院,眼科; | 5248.88 | 67 | 2022 | Single-cell RNA sequencing depicts the local cell landscape in thyroid-associated ophthalmopathy | CELL REP MED | 苏文如,中山大学,中山眼科中心,眼科; | 5240.48 | 68 | 2022 | TNF-alpha stimulation enhances the neuroprotective effects of gingival MSCs derived exosomes in retinal ischemia-reperfusion injury via the MEG3/miR-21a-5p axis | BIOMATERIALS | 卓业鸿,中山大学,中山眼科中心,眼科; | 5159.54 | 69 | 2022 | Integrating single-cell sequencing data with GWAS summary statistics reveals CD16+monocytes and memory CD8+T cells involved in severe COVID-19 | GENOME MED | 苏建忠,中国科学院大学,温州研究院; | 5144.45 | 70 | 2022 | miR-204-containing exosomes ameliorate GVHD-associated dry eye disease | SCI ADV | 柳夏林,中山大学,中山眼科中心,眼科; | 5142.22 | 71 | 2022 | In-situ forming PEG-engineering hydrogels with anti-fouling characteristics as an artificial vitreous body | CHEM ENG J | 张明,四川大学,华西医院,眼科; | 5140.36 | 72 | 2022 | Neovascularization-directed bionic eye drops for noninvasive renovation of age-related macular degeneration | CHEM ENG J | 张含,中国医科大学,附属第一医院,眼科; | 5140.36 | 73 | 2022 | Nutrient capsules maintain tear film homeostasis for human corneal lenticule transplantation | CHEM ENG J | 周行涛,复旦大学上海医学院,眼耳鼻喉科医院,眼科; | 5140.36 | 74 | 2022 | Myopia incidence and lifestyle changes among school children during the COVID-19 pandemic: a population-based prospective study | BRIT J OPHTHALMOL | Yam, Jason C. S.,香港中文大学; | 5121.65 | 75 | 2022 | Torin 1 alleviates impairment of TFEB-mediated lysosomal biogenesis and autophagy in TGFBI (p.G623_H626del)-linked Thiel-Behnke corneal dystrophy | AUTOPHAGY | 刘平,哈尔滨医科大学,附属第一医院,眼科; | 5084.55 | 76 | 2022 | Glaucoma Characterization by Machine Learning of Tear Metabolic Fingerprinting | SMALL METHODS | 周民稳,上海交通大学医学院,第一人民医院,眼科临床医学中心; | 5064.59 | 77 | 2022 | Monitoring Retinoblastoma by Machine Learning of Aqueous Humor Metabolic Fingerprinting | SMALL METHODS | 范先群,上海交通大学医学院,医学院本部; | 5064.59 | 78 | 2022 | Facile formation of injectable quaternized chitosan/tannic acid hydrogels with antibacterial and ROS scavenging capabilities for diabetic wound healing | INT J BIOL MACROMOL | 沈建良,温州医科大学,附属眼视光学院; | 5048.00 | 79 | 2022 | Atomically Thin TaSe2 Film as a High-Performance Substrate for Surface-Enhanced Raman Scattering | SMALL | 王毅,温州医科大学; | 4979.66 | 80 | 2022 | Killing three birds with one stone: Near-infrared light triggered nitric oxide release for enhanced photodynamic and anti-inflammatory therapy in refractory keratitis | BIOMATERIALS | 王佰亮,温州医科大学,附属眼视光医院,眼科; | 4919.54 | 81 | 2022 | Intravenous route to choroidal neovascularization by macrophage-disguised nanocarriers for mTOR modulation | ACTA PHARM SIN B | 赵晨,复旦大学上海医学院,眼耳鼻喉科医院,眼科; | 4880.95 | 82 | 2022 | Artificial intelligence to detect malignant eyelid tumors from photographic images | NPJ DIGIT MED | 李中文,温州医科大学,宁波眼科医院; | 4820.61 | 83 | 2022 | Immune Checkpoint LAG3 and Its Ligand FGL1 in Cancer | FRONT IMMUNOL | 马楠,空军医科大学,唐都医院,眼科; | 4815.55 | 84 | 2022 | Aging weakens Th17 cell pathogenicity and ameliorates experimental autoimmune uveitis in mice | PROTEIN CELL | 苏文如,中山大学,中山眼科中心,眼科; | 4809.08 | 85 | 2022 | Melatonin prevents experimental central serous chorioretinopathy in rats | J PINEAL RES | 梁小玲,中山大学,中山眼科中心,眼科; | 4766.60 | 86 | 2022 | Liposome-based multifunctional nanoplatform as effective therapeutics for the treatment of retinoblastoma | ACTA PHARM SIN B | 黄一飞,中国人民解放军总医院,眼科; | 4760.95 | 87 | 2022 | Nanoporous Gold Ring-Integrated Photothermal Intraocular Lens for Active Prevention of Posterior Capsular Opacification | SMALL | 陈伟蓉,中山大学,中山眼科中心,眼科; | 4739.66 | 88 | 2022 | Reconstructing auto tissue engineering lamellar cornea with aspartic acid modified acellular porcine corneal stroma and preconditioned limbal stem cell for corneal regeneration | BIOMATERIALS | 万鹏霞,中山大学,附属第一医院,眼科; | 4679.54 | 89 | 2022 | DrABC: deep learning accurately predicts germline pathogenic mutation status in breast cancer patients based on phenotype data | GENOME MED | 苏建忠,中国科学院大学,温州研究院; | 4664.45 | 90 | 2022 | Mutation of SLC7A14 causes auditory neuropathy and retinitis pigmentosa mediated by lysosomal dysfunction | SCI ADV | 金子兵,首都医科大学,附属北京同仁医院,北京市眼科研究所（眼科）; | 4662.22 | 91 | 2022 | Fe saponite, a layered silicate for reversible lithium-ions storage with large diffusion coefficient | J ENERGY CHEM | 王开杰,首都医科大学,附属北京同仁医院,眼科; | 4615.15 | 92 | 2022 | Design of a Novel Fab-Like Antibody Fragment with Enhanced Stability and Affinity for Clinical use | SMALL METHODS | 洪佳旭,复旦大学上海医学院,眼耳鼻喉科医院,眼科; | 4584.59 | 93 | 2022 | 4D printed orbital stent for the treatment of enophthalmic invagination | BIOMATERIALS | 原慧萍,哈尔滨医科大学,附属第二医院,眼科; | 4559.54 | 94 | 2022 | Nanocapping-enabled charge reversal generates cell-enterable endosomal-escapable bacteriophages for intracellular pathogen inhibition | SCI ADV | 庞燕,上海交通大学医学院,第九人民医院,眼科; | 4542.22 | 95 | 2022 | Anti-PANoptosis is involved in neuroprotective effects of melatonin in acute ocular hypertension model | J PINEAL RES | 黄晶晶,中山大学,中山眼科中心,青光眼专科; | 4526.60 | 96 | 2022 | Centrifugally concentric ring-patterned drug-loaded polymeric coating as an intraocular lens surface modification for efficient prevention of posterior capsular opacification | ACTA BIOMATER | 林全愧,温州医科大学,附属眼视光医院,眼科; | 4485.79 | 97 | 2022 | Cis-regulatory chromatin loops analysis identifies GRHL3 as a master regulator of surface epithelium commitment | SCI ADV | 欧阳宏,中山大学,中山眼科中心,眼科学国家重点实验室; | 4422.22 | 98 | 2022 | Wnt inhibitory factor 1 ameliorated diabetic retinopathy through the AMPK/mTOR pathway-mediated mitochondrial function | FASEB J | 许惠卓,中南大学,湘雅医院; | 4413.39 | 99 | 2022 | Evaluation of the influences of low dose polybrominated diphenyl ethers exposure on human early retinal development | ENVIRON INT | 徐海伟,陆军军医大学,西南医院,眼科; | 4401.10 | 100 | 2022 | Cascade two-stage tumor re-oxygenation and immune re-sensitization mediated by self-assembled albumin-sorafenib nanoparticles for enhanced photodynamic immunotherapy | ACTA PHARM SIN B | 沈建良,温州医科大学,附属眼视光学院; | 4400.95 |
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