2022年度中国神经内科领域高价值论文TOP100
以往我们对一篇论文的价值评估，是通过期刊影响因子或被引频次来判断，这种采用单一指标评判论文的学术价值因有失偏颇而广受诟病。北京同舟云网络信息技术有限公司创立了一种优选算法，综合考虑Metrics 期刊评分、论文被引频次、文献类型以及论文发表时间等多种因素，对每篇论文进行深度解析与计算，并赋予分值，以量化每篇论文的学术价值和影响力。本推荐表是在系统全面准确地统计中国机构作者发表的神经内科领域国际论文的基础上（说明神经内科领域专家为主要完成人发表的全部论文均入选，不再筛选论文的内容主题），对每篇论文依上述方法进行计算并赋分排名而得出的，供相关学者学习、评判、参考和借鉴。
序号 | 年份 | 标题 | 期刊 | 主要完成人 | 论文评分 | 1 | 2022 | Trial of Endovascular Treatment of Acute Basilar-Artery Occlusion | NEW ENGL J MED | 胡伟,中国科学技术大学;附属第一医院;神经内科; | 119508.98 | 2 | 2022 | Effect of Intravenous Tirofiban vs Placebo Before Endovascular Thrombectomy on Functional Outcomes in Large Vessel Occlusion Stroke The RESCUE BT Randomized Clinical Trial | JAMA-J AM MED ASSOC | 杨清武,陆军军医大学,新桥医院,神经内科; | 102765.23 | 3 | 2022 | Effect of Remote Ischemic Conditioning vs Usual Care on Neurologic Function in Patients With Acute Moderate Ischemic Stroke The RICAMIS Randomized Clinical Trial | JAMA-J AM MED ASSOC | 陈会生,北部战区总医院,,神经内科; | 102525.23 | 4 | 2022 | Structures and mechanisms of the Arabidopsis auxin transporter PIN3 | NATURE | 郭江涛,浙江大学,邵逸夫医院; | 34532.12 | 5 | 2022 | Bone marrow hematopoiesis drives multiple sclerosis progression | CELL | 刘强,天津医科大学,总医院,神经内科; | 33277.41 | 6 | 2022 | Emerging degrader technologies engaging lysosomal pathways | CHEM SOC REV | 鲁伯埙,复旦大学,生命科学学院; | 28812.93 | 7 | 2022 | Safety and efficacy of three enteral feeding strategies in patients with severe stroke in China (OPENS): a multicentre, prospective, randomised, open-label, blinded-endpoint trial | LANCET NEUROL | 江文,空军军医大学,西京医院,神经内科; | 28506.34 | 8 | 2022 | Depression compromises antiviral innate immunity via the AVP-AHI1-Tyk2 axis | CELL RES | 徐兴顺,苏州大学,附属第一医院,神经内科; | 20068.87 | 9 | 2022 | Article Microglia-derived PDGFB promotes neuronal potassium currents to suppress basal sympathetic tonicity and limit hypertension | IMMUNITY | 谷岩,浙江大学,基础医学院; | 18823.72 | 10 | 2022 | Thrombin induces ACSL4-dependent ferroptosis during cerebral ischemia/reperfusion | SIGNAL TRANSDUCT TAR | 雷鹏,四川大学,华西医院,神经内科; | 17786.58 | 11 | 2022 | Endovascular Treatment Versus Best Medical Management in Acute Basilar Artery Occlusion Strokes: Results From the ATTENTION Multicenter Registry | CIRCULATION | 胡伟,中国科学技术大学,附属第一医院,神经内科; | 17330.91 | 12 | 2022 | Targeting polarized phenotype of microglia via IL6/JAK2/STAT3 signaling to reduce NSCLC brain metastasis | SIGNAL TRANSDUCT TAR | 王伟,华中科技大学,同济医院,神经内科; | 16106.58 | 13 | 2022 | Conformational strains of pathogenic amyloid proteins in neurodegenerative diseases | NAT REV NEUROSCI | 刘聪,中国科学院; | 15978.07 | 14 | 2022 | Signaling pathways involved in ischemic stroke: molecular mechanisms and therapeutic interventions | SIGNAL TRANSDUCT TAR | 王伟,华中科技大学,同济医院,神经内科; | 15866.58 | 15 | 2022 | FSAP aggravated endothelial dysfunction and neurological deficits in acute ischemic stroke due to large vessel occlusion | SIGNAL TRANSDUCT TAR | 王伟,华中科技大学,同济医院,神经内科; | 15866.58 | 16 | 2022 | One-Year Trajectory of Cognitive Changes in Older Survivors of COVID-19 in Wuhan, China A Longitudinal Cohort Study | JAMA NEUROL | 王延江,陆军军医大学,大坪医院,神经内科; | 13779.83 | 17 | 2022 | Neuroinflammation in mild respiratory COVID-19: insights into cognitive impairment in milder cases | MILITARY MED RES | 王丽华,哈尔滨医科大学,附属第二医院,神经内科; | 13694.01 | 18 | 2022 | Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications | MED RES REV | 雷鹏,四川大学,华西医院,神经内科; | 11807.03 | 19 | 2022 | Efficacy and safety of three new oral antiviral treatment (molnupiravir, fluvoxamine and Paxlovid) for COVID-19: a meta-analysis | ANN MED | 冯占辉,贵州医科大学,临床医学院; | 11444.47 | 20 | 2022 | Distinct serotonergic pathways to the amygdala underlie separate behavioral features of anxiety | NAT NEUROSCI | 李晓明,浙江大学,医学院基础医学系; | 10579.24 | 21 | 2022 | Association of Ad26.COV2.S COVID-19 Vaccine With Presumptive Guillain-Barre Syndrome | JAMA-J AM MED ASSOC | 李海峰,山东大学,齐鲁医院,神经内科; | 10216.52 | 22 | 2022 | Intra-arterial Alteplase vs Placebo After Successful Thrombectomy and Functional Outcomes in Patients With Large Vessel Occlusion Acute Ischemic Stroke | JAMA-J AM MED ASSOC | 麦晖,湛江市中心人民医院,神经内一科; | 10192.52 | 23 | 2022 | CircOGDH Is a Penumbra Biomarker and Therapeutic Target in Acute Ischemic Stroke | CIRC RES | 徐安定,暨南大学,附属第一医院,神经内科; | 9386.14 | 24 | 2022 | Tau pathologies mediate the association of blood pressure with cognitive impairment in adults without dementia: The CABLE study | ALZHEIMERS DEMENT | 郁金泰,复旦大学上海医学院,华山医院,神经内科; | 8883.45 | 25 | 2022 | Bioactive Nanoenzyme Reverses Oxidative Damage and Endoplasmic Reticulum Stress in Neurons under Ischemic Stroke | ACS NANO | 徐安定,暨南大学,附属第一医院,神经内科; | 8672.13 | 26 | 2022 | Endothelial BACE1 Impairs Cerebral Small Vessels via Tight Junctions and eNOS | CIRC RES | 程忻,复旦大学上海医学院,华山医院,神经内科; | 8426.14 | 27 | 2022 | Ferroptosis promotes T-cell activation-induced neurodegeneration in multiple sclerosis | CELL MOL IMMUNOL | 雷鹏,四川大学,华西医院,神经内科; | 8280.45 | 28 | 2022 | Mild cognitive impairment among rural-dwelling older adults in China: A community-based study | ALZHEIMERS DEMENT | 杜怡峰,山东省立医院,,神经内科; | 7923.45 | 29 | 2022 | A metabolite panel that differentiates Alzheimer's disease from other dementia types | ALZHEIMERS DEMENT | 贾龙飞,首都医科大学,宣武医院,神经内科; | 7923.45 | 30 | 2022 | A combination model of AD biomarkers revealed by machine learning precisely predicts Alzheimer's dementia: China Aging and Neurodegenerative Initiative (CANDI) study | ALZHEIMERS DEMENT | 申勇,中国科学技术大学,生命学院; | 7683.45 | 31 | 2022 | Association between Alzheimer's disease and risk of cancer: A retrospective cohort study in Shanghai, China | ALZHEIMERS DEMENT | 王刚,上海交通大学医学院,瑞金医院,神经内科; | 7683.45 | 32 | 2022 | Tai Chi enhances cognitive training effects on delaying cognitive decline in mild cognitive impairment | ALZHEIMERS DEMENT | 陈生弟,上海交通大学医学院,瑞金医院,神经内科; | 7323.45 | 33 | 2022 | Hypothalamus-habenula potentiation encodes chronic stress experience and drives depression onset | NEURON | 崔一卉,浙江大学,附属邵逸夫医院; | 7271.12 | 34 | 2022 | Education, neighborhood environment, and cognitive decline: Findings from two prospective cohort studies of older adults in China | ALZHEIMERS DEMENT | 崔梅,复旦大学上海医学院,华山医院,神经内科; | 7203.45 | 35 | 2022 | Binaural processing deficit and cognitive impairment in Alzheimer's disease | ALZHEIMERS DEMENT | 唐毅,首都医科大学,宣武医院,神经内科; | 7203.45 | 36 | 2022 | Dose-response relationship between late-life physical activity and incident dementia: A pooled analysis of 10 cohort studies of memory in an international consortium | ALZHEIMERS DEMENT | 丁玎,复旦大学上海医学院,华山医院,神经内科; | 7203.45 | 37 | 2022 | The impacts of health insurance and resource on the burden of Alzheimer's disease and related dementias in the world population | ALZHEIMERS DEMENT | 王刚,上海交通大学医学院,瑞金医院,神经内科; | 7203.45 | 38 | 2022 | Associations of grip strength, walking pace, and the risk of incident dementia: A prospective cohort study of 340212 participants | ALZHEIMERS DEMENT | 郁金泰,复旦大学上海医学院,华山医院,神经内科; | 7203.45 | 39 | 2022 | Anosmia, mild cognitive impairment, and biomarkers of brain aging in older adults | ALZHEIMERS DEMENT | 杜怡峰,山东省立医院,,神经内科; | 7203.45 | 40 | 2022 | Lack of bidirectional association between age-related macular degeneration and Alzheimer's disease: A Mendelian randomization study | ALZHEIMERS DEMENT | 沈璐,中南大学,湘雅医院,神经内科; | 7203.45 | 41 | 2022 | Se-Containing MOF Coated Dual-Fe-Atom Nanozymes With Multi-Enzyme Cascade Activities Protect Against Cerebral Ischemic Reperfusion Injury | ADV FUNCT MATER | 杨弋,吉林大学,白求恩第一医院,神经内科医疗组; | 7201.62 | 42 | 2022 | Regulation of neuroinflammation with GLP-1 receptor targeting nanostructures to alleviate Alzheimer's symptoms in the disease models | NANO TODAY | 邱伟,中山大学,附属第三医院,神经科; | 6830.04 | 43 | 2022 | A visual circuit related to the periaqueductal gray area for the antinociceptive effects of bright light treatment | NEURON | 任超然,暨南大学,粤港澳中枢神经再生研究院; | 6791.12 | 44 | 2022 | TRIM21 regulates pyroptotic cell death by promoting Gasdermin D oligomerization | CELL DEATH DIFFER | 陈向军,复旦大学上海医学院,华山医院,神经内科; | 6688.88 | 45 | 2022 | Systemic low-grade inflammation and depressive symptomology at chronic phase of ischemic stroke: The chain mediating role of fibrinogen and neutrophil counts | BRAIN BEHAV IMMUN | 朱遂强,华中科技大学,同济医学院附属同济医院,神经内科; | 6541.06 | 46 | 2022 | Regulation of Synovial Macrophages Polarization by Mimicking Efferocytosis for Therapy of Osteoarthritis | ADV FUNCT MATER | 张志珺,东南大学,中大医院,神经内科; | 6481.62 | 47 | 2022 | Tau modification by the norepinephrine metabolite DOPEGAL stimulates its pathology and propagation | NAT STRUCT MOL BIOL | 张振涛,武汉大学,人民医院,神经内科; | 6292.68 | 48 | 2022 | Recurrent circadian circuitry regulates central brain activity to maintain sleep | NEURON | 郭方,浙江大学,神经科学研究所; | 6191.12 | 49 | 2022 | Performance evaluation of differential splicing analysis methods and splicing analytics platform construction | NUCLEIC ACIDS RES | 赵贵虎,中南大学,湘雅医院,老年神经内科; | 6152.36 | 50 | 2022 | Peripheral immunity is associated with the risk of incident dementia | MOL PSYCHIATR | 郁金泰,复旦大学上海医学院,华山医院,神经内科; | 6034.87 | 51 | 2022 | Ruthenium complexes boost NK cell immunotherapy via sensitizing triple-negative breast cancer and shaping immuno-microenvironment | BIOMATERIALS | 陈填烽,暨南大学; | 5999.54 | 52 | 2022 | Expanding the phenotype and genotype spectra of PLIN4-associated myopathy with rimmed ubiquitin-positive autophagic vacuolation | ACTA NEUROPATHOL | 王柠,福建医科大学,附属第一医院,神经内科; | 5853.88 | 53 | 2022 | Adaptive structural changes in the motor cortex and white matter in Parkinson's disease | ACTA NEUROPATHOL | 刘军,上海交通大学医学院,瑞金医院,神经内科; | 5853.88 | 54 | 2022 | Bioactive Nanoenzyme Reverses Oxidative Damage and Endoplasmic Reticulum Stress in Neurons under Ischemic Stroke | ACS NANO | 徐安定,暨南大学,附属第一医院,神经内科; | 5792.13 | 55 | 2022 | Neutrophil Nanovesicle Protects against Experimental Autoimmune Encephalomyelitis through Enhancing Myelin Clearance by Microglia | ACS NANO | 邱伟,中山大学,附属第三医院,神经科; | 5792.13 | 56 | 2022 | Comparisons of clinical phenotype, radiological and laboratory features, and therapy of neuromyelitis optica spectrum disorder by regions: update and challenges | AUTOIMMUN REV | 祝捷,吉林大学,第一医院,神经内科; | 5766.47 | 57 | 2022 | Light-Activated Gold-Selenium Core-Shell Nanocomposites with NIR-II Photoacoustic Imaging Performances for Heart-Targeted Repair | ACS NANO | 范存东,山东第一医科大学; | 5672.13 | 58 | 2022 | Brain regions susceptible to alpha-synuclein spreading | MOL PSYCHIATR | 雷鹏,四川大学,华西医院,神经内科; | 5554.87 | 59 | 2022 | ATP7B gene therapy of autologous reprogrammed hepatocytes alleviates copper accumulation in a mouse model of Wilson's disease | HEPATOLOGY | 王晓平,上海交通大学医学院,同仁医院,神经内科; | 5540.99 | 60 | 2022 | Therapeutic potential of chimeric antigen receptor based therapies in autoimmune diseases | AUTOIMMUN REV | 罗苏珊,复旦大学上海医学院,华山医院,神经内科; | 5526.47 | 61 | 2022 | The advances of post-stroke depression: 2021 update | J NEUROL | 刘新峰,东部战区总医院,,神经内科; | 5470.28 | 62 | 2022 | Biogeography of the large intestinal mucosal and luminal microbiome in cynomolgus macaques with depressive-like behavior | MOL PSYCHIATR | 谢鹏,重庆医科大学,附属永川医院,神经内科病房; | 5434.87 | 63 | 2022 | Potential therapeutic strategies in chronic inflammatory demyelinating polyradiculoneuropathy | AUTOIMMUN REV | 林洁,复旦大学上海医学院,华山医院,神经内科; | 5406.47 | 64 | 2022 | Reversing breast cancer bone metastasis by metal organic framework-capped nanotherapeutics via suppressing osteoclastogenesis | BIOMATERIALS | 陈填烽,暨南大学; | 5399.54 | 65 | 2022 | Cognitive performance protects against Alzheimer's disease independently of educational attainment and intelligence | MOL PSYCHIATR | 刘桂友,首都医科大学,北京脑重大疾病研究院; | 5314.87 | 66 | 2022 | In situ-transition nanozyme triggered by tumor microenvironment boosts synergistic cancer radio-/chemotherapy through disrupting redox homeostasis | BIOMATERIALS | 陈填烽,暨南大学; | 5279.54 | 67 | 2022 | The CGG repeat expansion in RILPL1 is associated with oculopharyngodistal myopathy type 4 | AM J HUM GENET | 王朝霞,北京大学,第一医院,神经内科; | 5216.63 | 68 | 2022 | Evaluation of early antibiotic use in patients with non-severe COVID-19 without bacterial infection | INT J ANTIMICROB AG | 熊念,华中科技大学,附属协和医院,神经内科; | 5214.04 | 69 | 2022 | Liquid-liquid phase separation of RBGD2/4 is required for heat stress resistance in Arabidopsis | DEV CELL | 刘聪,中国科学院; | 5211.26 | 70 | 2022 | Nanoengineered on-demand drug delivery system improves efficacy of pharmacotherapy for epilepsy | SCI ADV | 汪仪,浙江大学; | 5142.22 | 71 | 2022 | Loss of microglial EED impairs synapse density, learning, and memory | MOL PSYCHIATR | 唐毅,首都医科大学,宣武医院,神经内科; | 5074.87 | 72 | 2022 | An entorhinal-visual cortical circuit regulates depression-like behaviors | MOL PSYCHIATR | 谢鹏,重庆医科大学,附属永川医院,神经内科病房; | 5074.87 | 73 | 2022 | Identifying causal genes for depression via integration of the proteome and transcriptome from brain and blood | MOL PSYCHIATR | 郁金泰,复旦大学上海医学院,华山医院,神经内科; | 5074.87 | 74 | 2022 | Structural mechanisms of TRPV2 modulation by endogenous and exogenous ligands | NAT CHEM BIOL | 杨帆,浙江大学,基础医学院; | 5028.38 | 75 | 2022 | Promotion of row 1-specific tip complex condensates by Gpsm2-G alpha i provides insights into row identity of the tallest stereocilia | SCI ADV | 王朝,中国科学技术大学,生命科学与医学部; | 5022.22 | 76 | 2022 | RTN4/Nogo-A-S1PR2 negatively regulates angiogenesis and secondary neural repair through enhancing vascular autophagy in the thalamus after cerebral cortical infarction | AUTOPHAGY | 曾进胜,中山大学,附属第一医院,神经内科; | 4964.55 | 77 | 2022 | Sleep, physical activity, sedentary behavior, and risk of incident dementia: a prospective cohort study of 431,924 UK Biobank participants | MOL PSYCHIATR | 郁金泰,复旦大学上海医学院,华山医院,神经内科; | 4954.87 | 78 | 2022 | Enhancing GluN2A-type NMDA receptors impairs long-term synaptic plasticity and learning and memory | MOL PSYCHIATR | 石云,南京大学,模式动物研究所; | 4954.87 | 79 | 2022 | Circular RNA circ-FoxO3 attenuates blood-brain barrier damage by inducing autophagy during ischemia/reperfusion | MOL THER | 徐安定,暨南大学,附属第一医院,神经内科; | 4954.26 | 80 | 2022 | Molnupiravir and Its Antiviral Activity Against COVID-19 | FRONT IMMUNOL | 范俊芬,首都医科大学,宣武医院,神经内科; | 4935.55 | 81 | 2022 | Cu2+-Chelatable and ROS-Scavenging MXenzyme as NIR-II-Triggered Blood-Brain Barrier-Crossing Nanocatalyst against Alzheimer's Disease | SMALL | 王剑虹,复旦大学上海医学院,华山医院,神经内科; | 4859.66 | 82 | 2022 | FOXP3+macrophage represses acute ischemic stroke-induced neural inflammation | AUTOPHAGY | 陆正齐,中山大学,附属第三医院,神经内科; | 4844.55 | 83 | 2022 | Dysfunction of AMPA receptor GluA3 is associated with aggressive behavior in human | MOL PSYCHIATR | 石云,南京大学,模式动物研究所; | 4834.87 | 84 | 2022 | Human antimicrobial peptide LL-37 contributes to Alzheimer's disease progression | MOL PSYCHIATR | 舒友生,中国科学院,上海脑研究所; | 4834.87 | 85 | 2022 | Emerging strategies for the genetic dissection of gene functions, cell types, and neural circuits in the mammalian brain | MOL PSYCHIATR | 何苗,复旦大学上海医学院,脑科学研究院; | 4834.87 | 86 | 2022 | Association of life course adiposity with risk of incident dementia: a prospective cohort study of 322,336 participants | MOL PSYCHIATR | 郁金泰,复旦大学上海医学院,华山医院,神经内科; | 4834.87 | 87 | 2022 | Transcranial alternating current stimulation for treating depression: a randomized controlled trial | BRAIN | 王玉平,首都医科大学,宣武医院,神经内科; | 4780.09 | 88 | 2022 | SPY1 inhibits neuronal ferroptosis in amyotrophic lateral sclerosis by reducing lipid peroxidation through regulation of GCH1 and TFR1 | CELL DEATH DIFFER | 丰宏林,哈尔滨医科大学,脑缺血研究室,神经内科; | 4768.88 | 89 | 2022 | Multiattention Adaptation Network for Motor Imagery Recognition | IEEE T SYST MAN CY-S | 巫嘉陵,天津市环湖医院,,神经内科; | 4678.73 | 90 | 2022 | Tau accelerates alpha-synuclein aggregation and spreading in Parkinson's disease | BRAIN | 张振涛,武汉大学,人民医院,神经内科; | 4660.09 | 91 | 2022 | Deep learning-based automatic tumor burden assessment of pediatric high-grade gliomas, medulloblastomas, and other leptomeningeal seeding tumors | NEURO-ONCOLOGY | 杨利,中南大学,湘雅二医院,神经内科; | 4639.00 | 92 | 2022 | Clinical profile of fatal familial insomnia: phenotypic variation in 129 polymorphisms and geographical regions | J NEUROL NEUROSUR PS | 武力勇,首都医科大学,宣武医院,神经内科; | 4636.17 | 93 | 2022 | Blood-brain barrier Permeable nanoparticles for Alzheimer's disease treatment by selective mitophagy of microglia | BIOMATERIALS | 石胜良,广西医科大学,附属第二医院,神经内科; | 4559.54 | 94 | 2022 | Associations of plasma soluble CD22 levels with brain amyloid burden and cognitive decline in Alzheimer's disease | SCI ADV | 王延江,陆军军医大学,大坪医院,神经内科; | 4542.22 | 95 | 2022 | Supplementary motor area driving changes of structural brain network in blepharospasm | BRAIN | 刘刚,中山大学,附属第一医院,神经内科; | 4540.09 | 96 | 2022 | Genetic regulatory and biological implications of the 10q24.32 schizophrenia risk locus | BRAIN | 罗雄剑,中国科学院,昆明动物研究所; | 4540.09 | 97 | 2022 | Vitality-Enhanced Dual-Modal Tracking System Reveals the Dynamic Fate of Mesenchymal Stem Cells for Stroke Therapy | SMALL | 王鹤,复旦大学,类脑智能科学与技术研究; | 4499.66 | 98 | 2022 | Exosomes derived from bone marrow mesenchymal stem cells protect the injured spinal cord by inhibiting pericyte pyroptosis | NEURAL REGEN RES | 贾延劼,郑州大学,第一附属医院; | 4445.22 | 99 | 2022 | Impact of drug treatment and drug interactions in post-stroke epilepsy | PHARMACOL THERAPEUT | 赵传胜,中国医科大学,附属第一医院,神经内科; | 4419.33 | 100 | 2022 | Mitigation of honokiol on fluoride-induced mitochondrial oxidative stress, mitochondrial dysfunction, and cognitive deficits through activating AMPK/PGC-1a/Sirt3 | J HAZARD MATER | 范华,河南科技大学,属第一医院; | 4375.65 |
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