Distribution of the macaques genus-specific Alu repeat AluMacYa3 in the MGMT gene orthologs of old world monkeys

Abstract

Aim. To follow the distribution and evolution of the macaques genus-specific Alu repeat AluMacYa3 in Cercopithecidae MGMT gene orthologs. Methods. The homology between nucleotide sequences has been determined by the BLAST 2.6.1 program. The results of the search and identification of MGE have been obtained by the CENSOR program. Results. It has been shown on the example of Cercopithecidae MGMT gene orthologs that the genus-specific Alu repeat AluMacYa3 is present not only in the intron sequences of macaques, but also in other representatives of the Old World monkeys and in its evolutionary history not a deletion degradation of nucleotide sequences, as it is in the case of species-specific Alu repeats, but a single nucleotide polymorphism is dominated. Conclusions. Thus, the macaque genus-specific Alu repeat AluMacYa3 has been identified in different representatives of the Old World monkeys and its evolutionary history combines nucleotide polymorphism and deletion degradation of nucleotide sequences.