Affiliation:
1. Department of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China
Abstract
Background: The surgical selection for patients with lumbar disc herniation (LDH) with
Modic changes (MCs) is still contentious. Percutaneous endoscopic lumbar discectomy via a
transforaminal approach (TF-PELD) as a representative minimally invasive spine surgery technique
for LDH has been standardized. However, its efficacy has not been thoroughly described in the
patients with LDH with MCs.
Objectives: The goal of this study was to assess the clinical outcomes of TF-PELD in the
treatment of LDH and MCs.
Study Design: Retrospective study.
Setting: Inpatient surgery center.
Methods: From January 2015 to December 2016, 276 patients with LDH showing normal or
MCs signals in their bone marrow in our hospital were enrolled in this retrospective study. All
patients suffered low back and leg pain because of LDH and underwent the TF-PELD procedure.
Clinical outcomes were assessed according to the Visual Analog Scale (VAS) for back pain and
leg pain, Oswestry Disability Index (ODI) for functional status assessment, and modified MacNab
criteria for patient satisfaction.
Results: A total of 182 patients showed normal intensity, 44 patients showed Modic type 1
signals, and 50 patients showed Modic type 2 signals before surgery. The postoperative VAS
and ODI scores were significantly improved compared with those preoperatively among the
groups. In the Modic type 1 and 2 signals groups, however, the postoperative VAS scores for
back pain and ODI scores showed an upward trend with the follow-up time extending. The
recurrence rates were 4.4%, 9.1%, and 8.0% in the normal, Modic type 1 and 2 signals groups,
respectively. The recurrence rates and satisfaction rates showed no significant difference among
the groups at the final follow-up.
Limitations: This study has a small sample size and the follow-up period was too short. There
is no comparison with other therapeutic options such as fusion surgery or the lack of any other
treatment.
Conclusions: TF-PELD is an option for treatment of patients with LDH even if the patients
show MCs. However, the postoperative back pain and functional status have the trend of
deterioration with the time extending in patients with MCs, especially in the Modic type 1
signals
Publisher
American Society of Interventional Pain Physicians
Subject
Anesthesiology and Pain Medicine
Cited by
1 articles.
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