On liver damage at generalized form of coxiellosis. Case report

Author:

Domashenko O. N.1,Slyusar E. A.2,Gridasov V. A.1

Affiliation:

1. Donetsk National Medical University named after M. Gorky, Donetsk

2. Central City Clinical Hospital № 1, Donetsk

Abstract

Disease case has been analyzed at 59 years old female patient, living in rural area. The disease progressed with long-time and high fever accompanied with liver damage including formation of abscesses. Anamnesis showed that raw milk was consumed. During 1.5 months, high steady fever, weakness, sweating and anorexia were observed, with further moderate pain in a right abdominal wing. The whole period of disease was noted with hepatomegaly, worsening leukocytosis, ESR 60 mm/hr, and moderate hyperenzymenia. SCT findings showed an inhomogene hypoechoic formation in a right hepatic lobe in segment’s projection 7, with sharp margins, dimension 3,0 2,2 cm, with 4 nearby liquor formations up to 1.2 cm in diameter. The percutaneous puncture biopsy, liquor formation aspiration and automatic trepanobiopsy of the tissue pattern of the formation under consideration. Cytological study revealed a non-specific inflammation with pus. Atypical cells not found. Histological findings: biopsy material from liver does contain a fibrous tissue with granulomatous inflammation. Complex detoxicating, metabolic and desensibilizing therapy was performed in combination with Ofloxacin, Meropenem (14 days), and Doxycycline (20 days). Diagnosed coxiellosis was confirmed with ELISA in titer 1:400/ОD 0,587 –ОD/0,726. The patient is fully recovered.

Publisher

SPRIDA

Subject

Infectious Diseases

Reference15 articles.

1. Leung-Shea C, Danaher PJ. Q fever in members of the United States armed forces returning from Iraq. Clin. Infect. Dis. 2006; 15(43): 77–82.

2. Karpenko SF. Vestnik novyh medicinskih tehnologij. 2013; 20 (3): 117-121(in Russian).

3. Yakovlev EA. [i dr.]. Problemy osobo opasnyh infekcij. 2015; 4:49–54 (in Russian).

4. Zykova T.A. Epidemiological features of coxiellosis in Rostov Region// Contemporary means for immunodiagnostics and immune and emergency prophylaxis of actual infections; Proceedings of the Conference, April 22-23, 2004, Saint Petersburg; p.p. 61-62.

5. Fetisova N.V. Ecological and epidemiological features of coxiellosis/ N/.FFetisova, M.T.Gafarova, “Vestnik Rossiiskoi akademii meditsinskikh nauk” (“Annals of the Russian academy of medical sciences”), 2008. Issue 7; p.p. 15-8.

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