Characteristics of measles immunity in students of the pediatric faculty of a medical university

Author:

Ivanov D. O.1,Timchenko V. N.1,Pavlova E. B.1,Barakina E. V.1,Chernova T. M.1,Pavlova N. V.1,Bulina O. V.1,Nazarova A. N.1

Affiliation:

1. Saint-Petersburg State Pediatric Medical University

Abstract

Objective: to evaluate the intensity of measles immunity in students of I–VI courses of the pediatric faculty of St. Petersburg State Medical University.Materials and methods: titers of antibodies to measles virus were determined in 986 students of I–VI courses in May –June 2019. The level of measles antibodies was determined by enzyme-linked immunosorbent assay.Results: positive (protective) titres of measles antibodies were detected in 555 people. (56.4%), the absence of measles immunity was found in 431 people. (43.6%), including 57 people. (5.8%) specific antibodies were not detected. The relationship between the level of collective immunity and the duration of the period after the last vaccination against measles was revealed.Conclusions: in the majority of examined students (96.2%), protective titers of measles antibodies remained for 10 years after the last vaccination. Subsequently, a significant decrease in the level of measles antibodies was noted. All students who do not have a protective IgG titer are shown measles vaccination with live measles vaccine in accordance with the instructions for use. 

Publisher

SPRIDA

Subject

Infectious Diseases

Reference23 articles.

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5. World Health Organization Regional Office for Europe (WHO/Europe). Fifth Meeting of the European Regional Verification Commission for Measles and Rubella Elimination (RVC) 24–26 October 2016. Copenhagen, Denmark. Copenhagen: WHO/Europe [Accessed 31 Aug 2017]. URL: http://www. euro.who.int/__data/assets/pdf _file/0005/330917/5th-RVCmeeting-report.pdf?ua=1).

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