Author:
S Sruthi,Dhavse Rasika,Sarvaiya Jignesh
Abstract
In bio-impedance analysis (BIA), high-frequency low-amplitude alternating current (AC) signals can incur time delays due to the capacitive nature of human cell membranes, and the characteristics of human tissues can be assessed from these delays in terms of phase changes. To accurately measure the phase changes, this work proposes a modified digital correlation-based phase measurement method. The accuracy of the general correlation technique is improved through digital direct synthesis (DDS) and digital correlation of unipolar square input signals. The proposed method is established through memory management and frequency adjustment. The result shows that, compared to the existing methods, the proposed method needs fewer hardware components, has better accuracy of 0.2° and higher frequency compatibility from 5 kHz to 1 MHz, and requires lower cost (140 USD). The method can be applied for the BIA of all types of tissues (recently used in COVID detection and care) and for the applications where efficient phase measurement is required.
Publisher
Taiwan Association of Engineering and Technology Innovation
Reference25 articles.
1. M. Sedlacek and M. Krumpholc, “Digital Measurement of Phase Difference—A Comparative Study of DSP Algorithms,” Metrology and Measurement Systems, vol. 12, no. 4, pp. 427-448, January 2005.
2. S. Grimnes and O. Martinsen, Bioimpedance and Bioelectricity Basics, London: Academic Press, 2008.
3. S. Sruthi, R. Dhavse, and J. N. Sarvaiya, “Precise, Portable and Wide Band Alternating Current Source for Extremely Low Current Values,” Analog Integrated Circuits and Signal Processing, vol. 102, no. 2, pp. 273-282, February 2020.
4. F. Simini and P. Bertemes-Filho, Bioimpedance in Biomedical Applications and Research, Cham: Springer International Publishing, 2018.
5. H. P. F. X. Moonen, F. J. L. Zanten, L. Driessen, V. de Smet, R. Slingerland-Boot, M. Mensink, et al., “Association of Bioelectric Impedance Analysis Body Composition and Disease Severity in COVID-19 Hospital Ward and ICU Patients: The BIAC-19 Study,” Clinical Nutrition, vol. 40, no. 4, pp. 2328-2336, October 2021.