Phase Transition Thermodynamic Properties Of 2-Methylquinoline, 2-Chloroquinoline And 2-Phenylquinoline

Abstract

Derivatives of quinoline are widely utilized in both industries and in healthcare. To understand the quinolines' quality and stability in usage, it is crucial to study their phase transition chemical thermodynamic characteristics. In this work, the phase transition thermodynamic characters of 2-methylquinoline (quinaldine), 2-chloroquinoline, and 2-phenylquinoline were investigated. Moreover, the sublimation/vaporization enthalpy of the compounds were determined the solution calorimetry-additivity scheme approach at 298.15 K. The solution calorimetry was applied to measure solution enthalpies of the compounds in benzene solvent at 298.15 K. While, the solvation enthalpy of the compounds were calculated additivity scheme approach. In addition, the transpiration method applied to estimate vapor pressure to temperature dependency to 2-Chloroquinoline. In consequence, the vapor pressure values with respect to temperature variation was determined to 2-Chloroquinoline compound for the first time. As a result, the phase transition chemical thermodynamic properties; enthalpy, entropy, and Gibbs energy for 2-methylquinoline, 2-chloroquinoline and 2-phenylquinoline were determined from crystalline/liquid to gas phase. Furthermore, in this work the thermochemical characteristics values of the studied compounds exhibited higher accuracy to those in literature data. Finally, the phase transition thermodynamically studied on 2-position of the quinoline compound, where it substituted to methyl, chloro and phenyl groups.