Hematological and Inflammatory Parameters to Predict the Develop Surgical Site Infection After Cesarean Section

Abstract

Objective: This study seeks to illustrate the efficacy of inflammatory hematological markers in patients who develop site infections following a cesarean section, while also establishing reference values for these parameters. Methods: This retrospective, single-center study was conducted at Ordu University Training and Research Hospital from January 2016 to January 2023. A comparison was made between 42 cases where surgical site infection developed after cesarean section and 42 cases. The data for this study were obtained from hospital medical records, which encompass of demographic, general medical, obstetric, and neonatal information. Preoperative complete blood count (CBC) was included in the analysis. Results: Statistically significant differences were observed among preoperative hematological and inflammation markers, including "PLT, WBC, NOT, PCT, MLR, DNLR, NLO, PLO, MPVPR, LP, RDWPR, NLRNPR, SII. ROC analysis revealed that optimal cutoff values were statistically significant for most laboratory parameters and blood count-derived ratios in patients with post-Cesarean wound infection. The largest AUC for SII was 0.861 with the cut-off value of 892.03 (sensivity %76 and specifity %76). Conclusion: This article has revealed differences between hematological and inflammatory markers in patients developing complications at the incision site after cesarean section. To assess the risk of surgical site infection development and reduce morbidity and hospitalization durations, further research in this area is needed.