In-Vivo Measurements of Blood Flow Velocity Profiles in Canine Ilio-Femoral Anastomotic Bypass Grafts

Author:

Jones S. A.1,Giddens D. P.2,Loth F.1,Zarins C. K.3,Kajiya F.4,Morita I.4,Hiramatsu O.4,Ogasawara Y.4,Tsujioka K.4

Affiliation:

1. Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218

2. Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD 21218

3. Department of Surgery, Stanford University, Stanford, CA 94305-5450

4. Medical Engineering and Systems Cardiology, Kawasaki Medical School, Kurashiki City, Japan

Abstract

In-vivo velocity profiles were recorded with a 20 MHz, 80-channel pulsed Doppler ultrasound velocimeter in canine end-to-side ilio-femoral anastomotic grafts. The geometries were obtained from casts of the anastomotic region, and flow rates were measured with electromagnetic flow probes. Three cases reported here include a “standard” geometry, which was similar to previously studied in vitro models, a stenosed geometry, and a case with below average flow rate. Observed flow features include separation at the hood and toe, movement of the floor stagnation point, and skewed profiles in the proximal outflow segment. Out-of-plane curvature and lateral displacement of the anastomosis inlet appear to have a strong effect on the flow fields. In addition, compliance affects the instantaneous flow rates within the proximal and distal branches.

Publisher

ASME International

Subject

Physiology (medical),Biomedical Engineering

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