A Porous Media Approach for Bifurcating Flow and Mass Transfer in a Human Lung

Author:

Kuwahara Fujio1,Sano Yoshihiko1,Liu Jianjun2,Nakayama Akira3

Affiliation:

1. Department of Mechanical Engineering, Shizuoka University, 3-5-1 Johoku, Hamamatsu 432-8561, Japan

2. Department of Civil Engineering, Wuhan Polytechnic University, Hubei, Wuhan 430023, China

3. Department of Mechanical Engineering, Shizuoka University, 3-5-1 Johoku, Hamamatsu 432-8561, Japan; Department of Civil Engineering, Wuhan Polytechnic University, Hubei, Wuhan 430023, China

Abstract

A porous media approach was proposed to investigate the characteristics of the bifurcating airflow and mass transfer within a lung. The theory of porous media was introduced in order to deal with a large number of bifurcations and a vast scale difference resulting from bifurcations. Upon introducing a two-medium treatment for the air convection and the diffusion in its surrounding wall tissue, the oxygen mass transfer between the inhaling air and the tissue was considered along with the effects of the blood perfusion on the mass transfer within the tissue. The overall mass transfer resistance between the inlet of the trachea and the blood in the capillaries was obtained on the basis of the porous media approach. The analysis reveals that there exists the optimal number of the bifurcation levels, namely, 23, that yields the minimum overall mass transfer resistance for the mass transport from the external air to the red blood cells. The finding is consistent with Bejan’s constructal law, namely, that for a flow system to persist in time, it must evolve in such a way that it provides easier access to its currents.

Publisher

ASME International

Subject

Mechanical Engineering,Mechanics of Materials,Condensed Matter Physics,General Materials Science

Reference17 articles.

1. Constructal Theory of Flow Architecture of the Lungs;Reis;Med. Phys.

2. Asymmetric Flow in Symmetric Branched Structures;Andrade;Phys. Rev. Lett.

3. Interplay Between Geometry and Flow Distribution in an Airway Tree;Mauroy;Phys. Rev. Lett.

4. A Porous Medium Model of Alveolar Gas Diffusion;Koulich;J. Porous Media

5. Three-Dimensional Unsteady Simulation of Alveolar Respiration;Koulich;J. Biomed. Eng.

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