Flow Rate-Pressure Drop Relation in Coronary Angioplasty: Catheter Obstruction Effect-Reference-Cited by-同舟云学术

Flow Rate-Pressure Drop Relation in Coronary Angioplasty: Catheter Obstruction Effect

Published:1996-02-01 Issue:1 Volume:118 Page:83-89
ISSN:0148-0731
Container-title:Journal of Biomechanical Engineering
language:en
Short-container-title:

Author:

Back L. H.¹,Kwack E. Y.¹,Back M. R.²

Affiliation:

1. Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109

2. Department of Surgery, Harbor-UCLA Medical Center, Torrance, CA 90509

Abstract

Quantitative methods to measure the hemodynamic consequences of various endovascular interventions including balloon angioplasty are limited. Catheters measuring translesional pressure drops during balloon angioplasty procedures can cause flow blockage and thus inaccurate estimates of pre- and post-intervention flow rates. The purpose of this investigation was to examine the influence of the presence and size of an angioplasty catheter on measured mean pressure gradients across human coronary artery stenoses. Analytical flow modeling and in vitro experimental evidence, coupled with angiographic data on the dimensions and shape of stenotic vessel segments before and after angioplasty, indicated significant flow blockage effects with the catheter present.

Publisher

ASME International

Subject

Physiology (medical),Biomedical Engineering

Link

http://asmedigitalcollection.asme.org/biomechanical/article-pdf/118/1/83/5504383/83_1.pdf

Reference21 articles.

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2. Back L. H. , and DentonT. A., 1992, “Some Arterial Wall Shear Stress Estimates in Coronary Angioplasty,” Advances in Bioengineering, Vol. BDE 22, pp. 337–340.

3. Back L. H. , 1994, “Estimated Mean Flow Resistance Increase during Coronary Artery Catheterization,” J. Biomechanics, Vol. 27, pp. 169–175.

4. Back, M. R., White, R. A., Kwack, E. Y., and Back, L. H., “Hemodynamic Consequences of Stenoses Remodeling during Coronary Angioplasty,” In Preparation.

5. Cavaye D. M. , WhiteR. A., KopchokG. E., DonayreC. A., and BackM. R., 1992, “Intravascular Ultrasound Imaging: The New Standard for Guidance and Assessment of Endovascular Interventions?,” J. Clinical Laser Medicine & Surgery, Vol. 10, pp. 349–353.

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