A Systems Approach to Biomechanics, Mechanobiology, and Biotransport

Author:

Peirce-Cottler Shayn M.1,Sander Edward A.23,Fisher Matthew B.45,Deymier Alix C.6,LaDisa John F.78,O'Connell Grace9,Corr David T.10,Han Bumsoo11121314,Singh Anita15,Wilson Sara E.16,Lai Victor K.17,Clyne Alisa Morss18

Affiliation:

1. Department of Biomedical Engineering, University of Virginia , Charlottesville, VA 22903

2. Roy J. Carver Department of Biomedical Engineering, College of Engineering, 5629 Seamans Center, University of Iowa , Iowa City, IA 52242 ; , Iowa City, IA 52242

3. Department of Orthopedics and Rehabilitation, Carver College of Medicine, University of Iowa , Iowa City, IA 52242 ; , Iowa City, IA 52242

4. Joint Department of Biomedical Engineering, North Carolina State University , Raleigh, NC 27695 ; , Chapel Hill, NC 27514

5. Joint Department of Biomedical Engineering, University of North Carolina-Chapel Hill , Raleigh, NC 27695 ; , Chapel Hill, NC 27514

6. Department of Biomedical Engineering, University of Connecticut Health , Farmington, CT 06032

7. Department of Biomedical Engineering, Marquette University and the Medical College of Wisconsin , Wauwatosa, WI 53226 ; , Milwaukee, WI 53226

8. Department of Pediatrics, Division of Cardiology Herma Heart Institute, Children's Wisconsin and the Medical College of Wisconsin , Wauwatosa, WI 53226 ; , Milwaukee, WI 53226

9. Department of Mechanical Engineering, University of California-Berkeley , 6141 Etcheverry Hall, Berkeley, CA 94720

10. Department of Biomedical Engineering, Center for Modeling, Simulation, & Imaging in Medicine, Rensselaer Polytechnic Institute , 7042 Jonsson Engineering Center 110 8th Street, Troy, NY 12180

11. School of Mechanical Engineering, Purdue University , 585 Purdue Mall, West Lafayette, IN 47907 ; , West Lafayette, IN 47907 ; , 585 Purdue Mall, West Lafayette, IN 47907

12. Weldon School of Biomedical Engineering, Purdue University , 585 Purdue Mall, West Lafayette, IN 47907 ; , West Lafayette, IN 47907 ; , 585 Purdue Mall, West Lafayette, IN 47907

13. Center for Cancer Research, Purdue University , 585 Purdue Mall, West Lafayette, IN 47907 ; , West Lafayette, IN 47907 ; , 585 Purdue Mall, West Lafayette, IN 47907

14. Purdue University West Lafayette

15. Bioengineering Department, Temple University , Philadelphia, PA 19122

16. Department of Mechanical Engineering, University of Kansas , 1530 W 15th Street, Lawrence, KS 66045

17. Department of Chemical Engineering, University of Minnesota Duluth , Duluth, MN 55812

18. Fischell Department of Bioengineering, University of Maryland , 8278 Paint Branch Drive, College Park, MD 20742

Abstract

Abstract The human body represents a collection of interacting systems that range in scale from nanometers to meters. Investigations from a systems perspective focus on how the parts work together to enact changes across spatial scales, and further our understanding of how systems function and fail. Here, we highlight systems approaches presented at the 2022 Summer Biomechanics, Bio-engineering, and Biotransport Conference in the areas of solid mechanics; fluid mechanics; tissue and cellular engineering; biotransport; and design, dynamics, and rehabilitation; and biomechanics education. Systems approaches are yielding new insights into human biology by leveraging state-of-the-art tools, which could ultimately lead to more informed design of therapies and medical devices for preventing and treating disease as well as rehabilitating patients using strategies that are uniquely optimized for each patient. Educational approaches can also be designed to foster a foundation of systems-level thinking.

Publisher

ASME International

Reference136 articles.

1. An Engineering Design Approach to Systems Biology;Integr. Biol. (Camb),2017

2. Mechanistic and Data-Driven Models of Cell Signaling: Tools for Fundamental Discovery and Rational Design of Therapy;Curr. Opin. Syst. Biol.,2021

3. Multiscale Computational Models of Cancer;Curr. Opin. Biomed. Eng.,2019

4. Differential Progressive Remodeling of Coronary and Cerebral Arteries and Arterioles in an Aortic Coarctation Model of Hypertension;Front. Physiol.,2012

5. Ensuring Congruency in Multiscale Modeling: Towards Linking Agent Based and Continuum Biomechanical Models of Arterial Adaptation;Ann. Biomed. Eng.,2011

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