Effect of Bone Mineral Content on the Tensile Properties of Cortical Bone: Experiments and Theory
Affiliation:
1. University of Medicine and Dentistry of New Jersey, SOM, Department of Osteosciences/Biomechanics, PCC Suite 102, Stratford, NJ 08084-1504 2. UMDNJ-SOM, Department of Osteosciences/Biomechanics, PCC Suite 102, Stratford, NJ 08084-1504 Phone: (856) 566-2731 Fax: (856) 566-2733
Abstract
The effect of mineral volume fraction on the tensile mechanical properties of cortical bone tissue is investigated by theoretical and experimental means. The mineral content of plexiform, bovine bone was lowered by 18% and 29% by immersion in fluoride solutions for 3 days and 12 days, respectively. The elastic modulus, yield strength and ultimate strength of bone tissue decreased, while the ultimate strain increased with a decrease in mineral content. The mechanical behavior of bone tissue was modeled by using a micro-mechanical shear lag theory consisting of overlapped mineral platelets reinforcing the organic matrix. The decrease in yield stress, by the 0.002 offset method, of the fluoride treated bones were matched in the theoretical curves by lowering the shear yield stress of the organic matrix. The failure criterion used was based on failure stresses determined from a failure envelope (Mohr’s circle), which was constructed using experimental data. It was found that the model predictions of elastic modulus got worse with a decrease in mineral content (being 7.9%, 17.2% and 33.0% higher for the control, 3-day and 12-day fluoride-treated bones). As a result, the developed theory could not fully predict the yield strain of bones with lowered mineral content, being 12.9% and 21.7% lower than the experimental values. The predicted ultimate stresses of the bone tissues with lower mineral contents were within ±10% of the experimental values while the ultimate strains were 12.7% and 26.3% lower than the experimental values. Although the model developed in this study did not take into account the presence of hierarchical structures, voids, orientation of collagen molecules and micro cracks, it still indicated that the mechanical properties of the organic matrix depend on bone mineral content.
Publisher
ASME International
Subject
Physiology (medical),Biomedical Engineering
Reference47 articles.
1. Currey, J. D.
, 1984, “Effects of Differences in Mineralization on the Mechanical Properties of Bone,” Philos. Trans. R. Soc. London, B304, pp. 509–518. 2. Currey, J. D.
, 1990, “Physical Characteristics Affecting the Tensile Failure Properties of Compact Bone,” J. Biomech., 23(8), pp. 837–844. 3. Martin, R. B., and Ishida, J., 1989, “The Relative Effects of Collagen Fiber Orientation, Porosity, Density, and Mineralization on Bone Strength,” J. Biomech., 22(5), pp. 419–426. 4. Martin, R. B., and Boardman, D. L., 1993, “The Effects of Collagen Fiber Orientation, Porosity, Density and Mineralization on Bovine Cortical Bone Bending Properties,” J. Biomech., 26(9), pp. 1047–1054. 5. Broz, J. J., Simske, S. J., and Greenberg, A. R., 1995, “Material and Compositional Properties of Selectively Demineralized Cortical Bone,” J. Biomech., 28, pp. 1357–1368.
Cited by
22 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
|
|