Miniature Pump for Treatment of Refractory Ascites Based on Local Magnetic Actuation

Author:

Garbin Nicolo1,Doyle Patrick2,Smith Byron3,Taylor Jesse G.4,Khan Mubashir H.5,Khalil Qasim6,Valdastri Pietro7

Affiliation:

1. Department of Mechanical Engineering, Vanderbilt University, Nashville, TN 37212 e-mail:

2. Medical Merge LLC, Brentwood, TN 37027 e-mail:

3. Senior Engineer, Medical Merge LLC, Brentwood, TN 37027 e-mail:

4. Gastroenterologist, Springfield, MO 65804 e-mail:

5. Gastroenterologist, Springfield, MO 65809 e-mail:

6. Hospital Medicine Consultant, Abu Dhabi, 112412, United Arab Emirates e-mail:

7. Chair in Robotics & Autonomous Systems, School of Electronic and Electrical Engineering, University of Leeds, Leeds, LS2 9JT, UK e-mail:

Abstract

This paper presents the design, fabrication, and experimental validation of a novel low-cost implantable pump for the treatment of refractory ascites (RA) based on local magnetic actuation (LMA). A reciprocating positive displacement pump displaces liquid unidirectionally through magnetic coupling with a magnetic controller placed on the outside of the patient's body. The proposed solution is intuitive to use given an alignment algorithm that exploits externally placed magnetic field sensors (MFS). The implantable device has a catheter-like shape, is electronic free (no on-board battery), has low fabrication cost (<8 USD), and is able to generate a flow-rate of 3.65 L/h while effectively pumping fluids with various viscosity (1–5.5 cP). RA is commonly treated via costly paracentesis or invasive surgical placement of a transjugular portosystemic shunt (TIPS). The proposed solution can be implanted with minimally invasive techniques and can be used on a daily basis to drain a set amount of liquid, without requiring recurrent hospital visits.

Publisher

ASME International

Subject

Biomedical Engineering,Medicine (miscellaneous)

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