A Hypothesized Mechanistic Model of Longitudinal Wall Motion at the Common Carotid Artery

Author:

Hao Zhili1,Reyonds Leryn2,Herre John M.3

Affiliation:

1. Department of Mechanical and Aerospace Engineering, Old Dominion University, Norfolk, VA 23529

2. Department of Human Movement Sciences, Old Dominion University, Norfolk, VA 23529

3. Eastern Virginia Medical School, Sentara Norfolk General Hospital, Norfolk, VA 23507

Abstract

Abstract By adopting a physics-physiology integrative approach, this work hypothesizes a mechanistic model of longitudinal wall motion ux(t) at the common carotid artery (CCA) and explores its antegrade amplitude ux0-ante and retrograde amplitude ux0-retro in systole for their clear implications. By examining the findings on ux(t) and other relevant findings on the cardiovascular (CV) physiology in the context of the physical essence of ux(t) and the CV system, a mechanistic model of ux(t) is hypothesized and formulated as a boundary-value problem of nonhomogeneous wave propagation in a semi-infinite domain. With the aid of findings on ux(t) and other related findings in the CV system, a scaling analysis of the boundary-value problem gives rise to two longitudinal arterial indices based on the two amplitudes: longitudinal elasticity Exx at the CCA being estimated from ux0-ante, and ux0-retro as an inverse indicator of the maximum base rotation of the left ventricle (LV) and a positive indicator of longitudinal elasticity at the ascending aorta (AA). The two arterial indices are qualitatively validated by their consistency with the effect of subclinical atherosclerosis and aging on the related parameters in the CV system. The implications of longitudinal elasticity to the LV function and energy transmission in the arterial tree are also discussed.

Publisher

ASME International

Subject

General Earth and Planetary Sciences,General Environmental Science

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3