Mixing Efficiency of Red Blood Cells With Magnetic Microspheres for a Hybrid Separation System-Reference-Cited by-同舟云学术

Mixing Efficiency of Red Blood Cells With Magnetic Microspheres for a Hybrid Separation System

Published:2008-09-01 Issue:3 Volume:2 Page:
ISSN:1932-6181
Container-title:Journal of Medical Devices
language:en
Short-container-title:

Author:

Haik Yousef¹²,Kanuri Sridhar³

Affiliation:

1. Center of Research Excellence in Nanobiosciences, University of North Carolina-Greensboro, Greensboro, NC 27402;

2. Department of Mechanical Engineering, United Arab Emirates University, P.O. Box 17555, Al Ain, United Arab Emirates

3. Center for Nanomagnetics and Biotechnology, Florida State University, Tallahassee, FL 32310

Abstract

The mixing efficiency of red blood cells and magnetic microspheres with red blood cell tagging ability is investigated using color particle image velocimetry. A hybrid separation system that utilizes centrifugation and magnetic separation is described. Magnetic microspheres are utilized to isolate the red cells from the buffy coat on a continuous basis. The effectiveness of red blood cell separation from the buffy coat in the hybrid system was improved over conventional centrifugal separation methods.

Publisher

ASME International

Subject

Biomedical Engineering,Medicine (miscellaneous)

Link

http://asmedigitalcollection.asme.org/medicaldevices/article-pdf/doi/10.1115/1.2975963/5748009/031006_1.pdf

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