Inertial Shear Forces and the Use of Centrifuges in Gravity Research. What is the Proper Control?-Reference-Cited by-同舟云学术

Inertial Shear Forces and the Use of Centrifuges in Gravity Research. What is the Proper Control?

Published:2003-06-01 Issue:3 Volume:125 Page:342-346
ISSN:0148-0731
Container-title:Journal of Biomechanical Engineering
language:en
Short-container-title:

Author:

van Loon Jack J. W. A.¹,Folgering Erik H. T. E.²,Bouten Carlijn V. C.³,Veldhuijzen J. Paul⁴,Smit Theo H.⁵

Affiliation:

1. Dutch Experiment Support Center (DESC), Oral Biology, ACTA Vrije Universiteit, van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands

2. TNO Insitute of Applied Physics, Dept. of Mechanical Engineering, P.O. Box 155, 2600 AD Delft, The Netherlands

3. Eindhoven University of Technology, Dept. Biomedical Engineering, Biomechanics & Tissue Engineering, P.O. Box 513, 5600 MB Eindhoven, The Netherlands

4. ACTA Vrije Universiteit, Dept. Oral Biology, Group of Oral Cell Biology, van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands

5. Dept. Physics and Medical Technology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands

Abstract

Centrifuges are used for 1×g controls in space flight microgravity experiments and in ground based research. Using centrifugation as a tool to generate an Earth like acceleration introduces unwanted inertial shear forces to the sample. Depending on the centrifuge and the geometry of the experiment hardware used these shear forces contribute significantly to the total force acting on the cells or tissues. The inertial shear force artifact should be dealt with for future experiment hardware development for Shuttle and the International Space Station (ISS) as well as for the interpretation of previous spaceflight and on-ground research data.

Publisher

ASME International

Subject

Physiology (medical),Biomedical Engineering

Link

http://asmedigitalcollection.asme.org/biomechanical/article-pdf/125/3/342/5767511/342_1.pdf

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