In Vitro Assessment of Knee Joint Biomechanics Using a Virtual Anterior Cruciate Ligament Reconstruction-Reference-Cited by-同舟云学术

In Vitro Assessment of Knee Joint Biomechanics Using a Virtual Anterior Cruciate Ligament Reconstruction

Published:2024-05-13 Issue:10 Volume:146 Page:
ISSN:0148-0731
Container-title:Journal of Biomechanical Engineering
language:en
Short-container-title:

Author:

Vakili Samira¹²^ORCID,Vivacqua Thiago³⁴,Getgood Alan⁵⁶⁷,Willing Ryan⁸⁹¹⁰

Affiliation:

1. School of Biomedical Engineering, Western University, 1151 Richmond Street N , London, ON N6A 5B9, Canada; , London, ON N6A 5B9, Canada

2. Western's Bone and Joint Institute, Western University , London, ON N6A 5B9, Canada; , London, ON N6A 5B9, Canada

3. Fowler Kennedy Sport Medicine Clinic, Department of Surgery, Western University, 3M Centre , London, ON N5A 3K7, Canada

4. Western University

5. Department of Orthopaedic Surgery, London Health Sciences Centre University Hospital , 339 Windermere Road, London, ON N6A 5A5, Canada; , 3M Centre, London, ON N5A 3K7, Canada; , London, ON N6A 5A5, Canada

6. Fowler Kennedy Sport Medicine Clinic, Department of Surgery, Western University , 339 Windermere Road, London, ON N6A 5A5, Canada; , 3M Centre, London, ON N5A 3K7, Canada; , London, ON N6A 5A5, Canada

7. Western's Bone and Joint Institute, Western University , 339 Windermere Road, London, ON N6A 5A5, Canada; , 3M Centre, London, ON N5A 3K7, Canada; , London, ON N6A 5A5, Canada

8. School of Biomedical Engineering, Western University, 1151 Richmond Street N , London, ON N6A 5B9, Canada; , 1151 Richmond Street N, London, ON N6A 5B9, Canada; , London, ON N6A 5A5, Canada

9. Department of Mechanical & Materials Engineering, Western University , London, ON N6A 5B9, Canada; , 1151 Richmond Street N, London, ON N6A 5B9, Canada; , London, ON N6A 5A5, Canada

10. Western's Bone and Joint Institute, Western University , London, ON N6A 5B9, Canada; , 1151 Richmond Street N, London, ON N6A 5B9, Canada; , London, ON N6A 5A5, Canada

Abstract

Abstract Understanding the biomechanical impact of injuries and reconstruction of the anterior cruciate ligament (ACL) is vital for improving surgical treatments that restore normal knee function. The purpose of this study was to develop a technique that enables parametric analysis of the effect of the ACL reconstruction (ACLR) in cadaver knees, by replacing its contributions with that of a specimen-specific virtual ACLR that can be enabled, disabled, or modified. Twelve ACLR reconstructed knees were mounted onto a motion simulator. In situ ACLR graft forces were measured using superposition, and these data were used to design specimen-specific virtual ACLRs that would yield the same ligament force-elongation behaviors. Tests were then repeated using the virtual ACLR in place of the real ACLR and following that in ACL deficient knee by disabling the virtual ACLR. In comparison to the ACL deficient state, the virtual ACLRs were able to restore knee stability to the same extent as real ACLRs. The average differences between the anterior tibial translation (ATT) of the virtual ACLR versus the real ACLR were +1.6 ± 0.9 mm (p = 0.4), +2.1 ± 0.4 mm (p = 0.4), and +1.0 ± 0.9 mm (p = 0.4) during Anterior drawer, Lachman and Pivot-shift tests, respectively, which is small in comparison to the full ATT range of motion (ROM) of these knees. Therefore, we conclude that a virtual ACLR can be used in place of real ACLR during biomechanical testing of cadaveric knees. This capability opens the door for future studies that can leverage parameterization of the ACLR for surgical design optimization.

Publisher

ASME International

Link

https://asmedigitalcollection.asme.org/biomechanical/article-pdf/146/10/101006/7341582/bio_146_10_101006.pdf

Reference58 articles.

1. The Cruciate Ligaments of the Knee Joint: Anatomical. Functional and Experimental Analysis;Clin. Orthop. Relat. Res.,1975

2. Treatment of Anterior Cruciate Ligament Injuries, Part I;Am. J. Sports Med.,2005

3. Prospective Evaluation of Arthroscopically Assisted Anterior Cruciate Ligament Reconstruction: Patellar Tendon Versus Semitendinosus and Gracilis Tendons;Am. J. Sports Med.,1991

4. Evaluation of a Simulated Pivot Shift Test: A Biomechanical Study;Knee Surg., Sports Traumatol., Arthroscopy,2012

5. Biomechanical Analysis of Simulated Clinical Testing and Reconstruction of the Anterolateral Ligament of the Knee;Am. J. Sports Med.,2015