Fabrication of Vascular Replicas From Magnetic Resonance Images

Author:

Friedman M. H.1,Kuban B. D.1,Schmalbrock P.2,Smith K.3,Altan T.3

Affiliation:

1. Biomedical Engineering Center, The Ohio State University, Columbus, OH 43210

2. Departments of Radiology and Mechanical Engineering, The Ohio State University, Columbus, OH 43210

3. Department of Mechanical Engineering, The Ohio State University, Columbus, OH 43210

Abstract

Image processing and Computer Numerical Controlled (CNC) machining techniques have been used to prepare a larger-than-life investment cast of an aortic bifurcation from magnetic resonance images of a replica of the vessel. The technique will facilitate experimental studies of vascular fluid dynamics and permit the in vitro reproduction of flows in living subjects.

Publisher

ASME International

Subject

Physiology (medical),Biomedical Engineering

Reference9 articles.

1. Bagchi, A., and Beaman, J. J., 1991, “Intelligent Design and Manufacturing for Prototyping,” ASME, New York.

2. Bresina, S. J., Vannier, M. W., Tepic, S., and Perren, S. M., 1990, “Automated Production of Custom Bone Replacements,” Proc. 12th Ann. Int’l Conf. IEEE EMBS, Philadelphia, pp. 385–386.

3. Friedman M. H. , 1993, “Arteriosclerosis Research Using Vascular Flow Models: From 2-D Branches to Compliant Replicas, ASME JOURNAL OF BIOMECHANICAL ENGINEERING, Vol. 115, pp. 595–601.

4. Friedman, M. H., Hacker, V. A., James, B. F., Kuban, B. D., Qin, J., and Schmalbrock, P., 1991, “MRI Measurement of Arterial Branch Geometry,” 1991 Biomechanics Symposium, Spilker, R. L. and Friedman, M. H., eds., ASME, New York, pp. 45–48.

5. Gowman, L. M., Rickey, D. W., Holdsworth, D. W., Caldwell, C. B., Frayne, R., Fenster, A., and Rutt, B. K., 1990, “Construction of a Geometrically Accurate Vascular Phantom for In Vitro MRI Flow Studies,” Proc. 9th Ann. Mtg SMRM, New York, p. 473.

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