分子機構に基づいた嗅覚医学の新規診断・検査法の開発の試み
Author:
Affiliation:
1. 東京大学大学院医学系研究科耳鼻咽喉科・頭頸部外科学分野
Publisher
Japan Rhinologic Society
Subject
General Medicine
Link
https://www.jstage.jst.go.jp/article/jjrhi/62/1/62_225/_pdf
Reference6 articles.
1. 1) Nagashima A, Touhara K: Enzymatic conversion of odorants in nasal mucus affects olfactory glomerular activation patterns and odor perception. J Neurosci 2010; 30: 16391–16398.
2. 2) Ijichi C, Wakabayashi H, Sugiyama S, et al: Metabolism of odorant molecules in human nasal/oral cavity affects the odorant perception. Chem Senses 2019; 44: 464–481.
3. 3) Ijichi C, Wakabayashi H, Sugiyama S, et al: Odorant metabolism of the olfactory cleft mucus in idiopathic olfactory impairment patients and healthy volunteers. Int Forum Allergy Rhinol 2022; 12: 293–301.
4. 4) Kondo K, Watanabe K, Sakamoto T, et al: Distribution and severity of spontaneous lesions in the neuroepithelium and Bowman’s glands in mouse olfactory mucosa: age-related progression. Cell Tissue Res 2009; 335: 489–503.
5. 5) Ijichi C, Kondo K, Kobayashi M, et al: Lipocalin 15 in the olfactory mucus is a biomarker for Bowman’s gland activity. Sci Rep 2022; 12: 9984.
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