Solvent-Dependent Phytochemical Richness and Antioxidant Efficacy of Ficus Carica Fruits: An Experimental Study

Abstract

Colorectal cancer and breast cancer is a major medical issue in Malaysia. Ficus Carica fruit has immense potential in the treatment of these cancers because of its antioxidant activity. This study aims to investigate the antioxidant activity of Ficus Carica fruit extract using various solvent extractions. The fruit extract of Ficus Carica was obtained using ethanolic, aqueous, and chloroform extraction methods. Preliminary phytochemical screening was conducted on ethanolic fig fruit extract. The ethanolic, aqueous, and chloroform fig fruit extracts were diluted to various concentrations and tested via antioxidant assays for total phenolic content, DPPH radical scavenging activity, and FRAP. Ethanolic extract of Ficus Carica fruit was observed to have the highest total phenolic content of 44.101± 0.005mg GAE/g DW, DPPH is the lowest IC50 of 0.005mg/ml and highest FRAP value of 29.423± 2.640 mg AAE/G DW at the lowest sample concentration, followed by water extraction, indicating that the highest antioxidant activity produced by the ethanolic Ficus Carica fruit extract. Ethanolic extract of Ficus Carica fruits exhibits potent antioxidant activity.