In the early nineteenth century, Edinburgh was the leading centre of medical education and research in Britain. It also laid claim to a thriving periodical culture. Literature and Medicine in the Nineteenth-Century Periodical Press investigates how Romantic periodicals cultivated innovative literary forms, ideologies and discourses that reflected and shaped medical culture in the nineteenth century. It examines several medically-trained contributors to Blackwood's Edinburgh Magazine, the most influential literary periodical of the time, and draws upon extensive archival and bibliographical research to reclaim these previously neglected medico-literary figures. Situating their work in relation to developments in medical and periodical culture, the book advances our understanding of how the nineteenth-century periodical press cross-fertilised medical and literary ideas. In the case of Blackwood’s, it is argued that the magazine’s distinctive Romantic ideology and experimental form enabled the development of an overtly ‘literary’ and humanistic popular medical culture, which participated in a wider critique of liberal Whig ideology in post-Enlightenment Scotland.