Affiliation:
1. School of Physical Education, Qiqihar University, Qiqihar, China
Abstract
To analyze the application of nanotechnology in the enhancement of the elastic strength of vital sign blood vessel walls, to study the effect of vascular endothelial growth factor (VEGF)-loaded multi-walled carbon nanotube (MWCNT) composite stents on blood vessels and to verify that nanotechnology can enhance the elastic strength of blood vessel walls. Through the purification of MWCNTs, the dispersion and stability of MWCNTs were improved, and functionalized MWCNTs were obtained. VEGF-loaded MWCNT composite scaffolds were constructed by using the infection method, and the mechanical properties of the composite scaffolds were tested. The higher the concentration of MWCNTs in the composite scaffold, the greater the maximum load and the stronger the ability of anti-elastic deformation. The 5% MWCNT composite scaffold had the best effect on promoting the growth of human umbilical vein endothelial cells. Compared with polycaprolactone scaffolds, MWCNT composite scaffolds had a more significant effect on promoting the proliferation of vascular cells and the endothelialization of blood vessels. The mechanical properties of MWCNT composite scaffolds are good, and they can increase endothelial cells and elastin. The application of MWCNT composite scaffolds in blood vessels can improve the elastic strength of blood vessels and provide reference for manufacturing better bone repair materials.