Endocrine mechanisms controlling the migratory disposition in birds

Abstract

On Earth, billions of birds make seasonal migrations every year. Some species fly thousands of kilometers, overcoming seas, mountains and deserts on their way. For migration to be successful, birds must have perfect mechanisms for controlling its beginning, duration and termination. On the way, birds have to make many decisions: how much in energy reserves to accumulate; when to depart, how long and in which direction to fly; how to select optimal weather conditions for flight; and, finally, when and where to terminate migration. Prior to migration, birds develop a migratory disposition – a suite of changes in physiology and behavior (e.g. migratory fattening and expression of nocturnal migratory activity) which are typical for this important life-history stage. Such physiological changes and migratory behavior are the subject of hormonal regulation. The central structure that controls activity of various hormonal systems and development of migratory disposition is the hypothalamic-pituitary system. The hypothalamus controls the secretion of regulatory hormones by the pituitary gland and these hormones, in turn, regulate the activity of downstream endocrine glands. It has been established that spring migratory disposition is triggered by an increasing photoperiod, which stimulates the production of testosterone, prolactin and modulates the signaling of thyroid hormones. In contrast, it is practically unknown how autumn migratory disposition develops when the photoperiod decreases and does not stimulate release of the abovementioned hormones. While in migratory disposition, the endocrine control of behavior on the smaller temporal scales (for example, the level of fuel accumulation, or decision to depart from a migratory stopover) is associated with the combined action of melatonin, corticosterone, insulin, glucagon, adipokines, and other hormones and neurotransmitters. In this review, I will describe the role of these hormones in the control of migratory traits, highlight the existing inconsistencies, and present possible ways to progress in this area of research. A knowledge of endocrine regulation of migratory behavior will help to predict the limits of species adaptability, explain current population trends, and inform conservation actions, which is especially important in the light of modern climate change and anthropogenic transformation of landscapes.