Associations of variability in body mass index with cardiovascular outcomes in the general population: A systematic review

Author:

Esfandiari Mohammad Ali1,Kazemzadeh Kimia2,Ansari Akram3,Alishiri Goharsharieh4,Afshari Shaghayegh5,Daliri Sepand2,Saleh Mohammadreza6,Balanian Sahar7,Tamannaeifar Rozhina8,Niazi Alireza9,Vosoughian Fatemeh10,Abdi Amir11,Mohebbi Mahnaz Bakhshi12,hosseini Reza Shah13,Foroughi Elaheh14,Deravi Niloofar10ORCID,Bafrani Melika Arab15,Asadigandomani Hassan16

Affiliation:

1. Student Research Committee, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran

2. Students’ Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran

3. Medical College, Shantou University, Shantou, Guandong, China

4. Students Research Committee, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran

5. Student Research Committee, School of Medicine, Shahroud University of Medical Sciences, Shahroud, Iran

6. Student Research Committee, Faculty of Medicine, Alborz University of Medical Sciences, Karaj, Iran

7. University of Welfare Sciences and Social Health, Tehran, Iran

8. Bioprocessing and Biodetection Laboratory, Department of Food Science and Technology, University of Tehran, Tehran, Iran

9. Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran

10. Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

11. Student Research Committee, School of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran

12. Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran

13. Faculty of Medicine, Istanbul Medipol University, Istanbul, Turkey

14. School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

15. Students’ Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, Iran

16. School of Medicine, Tehran University of Medical Science, Tehran, Iran

Abstract

In today's world, high variability of body mass index (BMI) is known as a significant global health problem that can lead to many negative impacts on the cardiovascular system, including atrial fibrillation (AF) and coronary heart disease. The current systematic review aims to elucidate the effect of variability in BMI on the risk of cardiovascular outcomes. Four databases, including PubMed, Scopus, MEDLINE, and CENTRAL, were searched. All related articles up to 10 June 2022, were obtained. Titles, abstracts, and full texts were reviewed. After screening abstracts and full texts, four articles were included in our study. In these four cohort studies, 7,038,873 participants from the USA and South Korea were involved. These articles generally considered the BMI and outcomes including cardiovascular disease, AF, and coronary heart disease. All these articles reported an association between the variability of BMI and increased risk of cardiovascular outcomes. Due to the negative impact of the high variability of BMI on the risk of cardiovascular outcomes, health policymakers and practitioners should pay more attention to the significant role of BMI in health problems and physicians might better check the variability of BMI visits to visit.

Publisher

SAGE Publications

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