The Relationship between Bioimpedance Analysis, Haemodynamic Parameters of Haemodialysis, Biochemical Parameters and Dry Weight

Abstract

Adequate fluid management plays an important role in the treatment of haemodialysis patients and the assessment of dry weight is important for efficient therapy. Fluid volume parameters were assessed in adults undergoing haemodialysis for end-stage renal disease, using whole-body multifrequency bioimpedance analysis (BIA), and their relationship to haemodynamic and biochemical parameters of haemodialysis was evaluated. Ultrafiltration volume was correlated with age, sodium, haemoglobin, extracellular water (ECW)/total body water (TBW) ratio and ECW/intracellular water (ICW) ratio. The ECW/TBW ratio was correlated with age, body mass index, dry weight, predialysis systolic and diastolic blood pressure, and ECW/total body weight ratio. The ECW/ICW ratio correlated with age, dry weight, TBW, albumin, adequacy of dialysis and urea removal ratio. The study demonstrated a close relationship between bioimpedance-derived fluid volume parameters and the haemodynamic and biochemical parameters of haemodialysis. It is concluded that multifrequency whole-body BIA may have clinical value in the estimation of dry weight and other haemodynamic parameters of haemodialysis and so may protect patients from the risks associated with under- or over-hydration.