Congestive Heart Failure Induced by the Combination of Atrial Fibrillation and Tricuspid Regurgitation

Author:

Kusaka K1,Takahashi T1,Kotajima N2,Sekiguchi K2,Fukumura Y2,Murakami M2,Kanda T1

Affiliation:

1. Department of General Medicine, Kanazawa Medical University, Ishikawa, Japan

2. Department of Laboratory Medicine and Medical Laboratory Center, Gunma University, Gunma, Japan

Abstract

Atrial fibrillation (AF) and tricuspid regurgitation (TR) may induce congestive heart failure (CHD). Using electrocardiography and echocardiography, we examined the clinical characteristics and haemodynamic findings in 100 patients with AF + TR + CHF, AF + TR, AF or TR. The fractional shortening in all groups with AF was significantly decreased compared with the TR group. The ejection fraction in patients with AF + TR + CHF was significantly lower than in the TR group. Twenty-four of the 72 patients with AF and TR (with or without CHF) were treated, and 13 were monitored for heart rate and severity of TR. Eight months after start of treatment the heart rate and typical symptoms and signs of heart failure had improved significantly in nine patients, but the severity of TR did not change. TR worsened in the remaining four patients but they did not develop CHF. Our results suggest that increased heart rate due to the combination of AF and TR could be responsible for CHF.

Publisher

SAGE Publications

Subject

Biochemistry, medical,Cell Biology,Biochemistry,General Medicine

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