Radiolabelled Stripped Mucin, SM3, Monoclonal Antibody for Immunoscintigraphy of Ovarian Tumours-Reference-Cited by-同舟云学术

Radiolabelled Stripped Mucin, SM3, Monoclonal Antibody for Immunoscintigraphy of Ovarian Tumours

Published:1990-04 Issue:2 Volume:5 Page:89-96
ISSN:1724-6008
Container-title:The International Journal of Biological Markers
language:en
Short-container-title:Int J Biol Markers

Author:

Granowska M.¹²,Mather S.J.¹²,Jobling T.³,Naeem M.¹,Burchell J²,Ylor-Papadimitriou J Ta²,Shepherd J³,Britton K.E.¹

Affiliation:

1. Departments of Nuclear Medicine, London

2. Imperial Cancer Research Fund, ICRF, Laboratories, London - England

3. Gynaecological Oncology, St. Bartholomew's Hospital, London

Abstract

A new monoclonal antibody, SM3, against stripped mucin core protein has been evaluated for the radioimmunoscintigraphy of ovarian cancer. It was radiolabelled with In-111, I-123 and Tc-99m and results showed a sensitivity of 95%, 100% and 100% and an accuracy of 73%, 86% and 100% for malignancy; respectively.

Publisher

SAGE Publications

Subject

Cancer Research,Clinical Biochemistry,Oncology,Pathology and Forensic Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/172460089000500208

Reference19 articles.

1. Conventional Radiology and Computed Tomography in Ovarian Cancer: Discussion Paper

2. Pitfalls in interpretation of computed tomography prior to second-look laparotomy in patients with ovarian cancer

3. Role of Ultrasound in the Management of Ovarian Carcinoma

4. TARGETING OF IODINE-123-LABELLED TUMOUR-ASSOCIATED MONOCLONAL ANTIBODIES TO OVARIAN, BREAST, AND GASTROINTESTINAL TUMOURS

5. Ovarian cancer

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